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On 20 April 2018, a laboratory accident led to a single worker being exposed to the Ebola virus, though he did not develop symptoms. [99] [100] 2022 DRC: EBOV 5 5 An outbreak in DRC began on April 23, and has killed 100% of those infected. [101] 2022 DRC: EBOV 1 1 A single case was confirmed in North Kivu. [102] 2025 Uganda: SUDV 9 1
Ebola, also known as Ebola virus disease (EVD) and Ebola hemorrhagic fever (EHF), is a viral hemorrhagic fever in humans and other primates, caused by ebolaviruses. [1] Symptoms typically start anywhere between two days and three weeks after infection. [3] The first symptoms are usually fever, sore throat, muscle pain, and headaches. [1]
Ansuvimab, sold under the brand name Ebanga, is a monoclonal antibody medication used for the treatment of Zaire ebolavirus (Ebolavirus) infection. [2] [3]The most common symptoms include fever, tachycardia (fast heart rate), diarrhea, vomiting, hypotension (low blood pressure), tachypnea (fast breathing) and chills; however, these are also common symptoms of Ebolavirus infection.
In March 2014, the World Health Organization (WHO) reported a major Ebola outbreak in Guinea, a western African nation, [1] the disease then rapidly spread to the neighboring countries of Liberia and Sierra Leone with smaller outbreaks occurring in Senegal, Nigeria, and Mali; the resulting West African Ebola virus epidemic is the largest Ebola outbreak (cases and deaths) ever documented.
No proven Ebola virus-specific treatment presently exists; [314] [315] however, measures can be taken to improve a patient's chances of survival. [316] Symptoms usually begin with a sudden influenza-like illness characterised by feeling tired, and pain in the muscles and joints. Later symptoms often include severe vomiting and diarrhoea.
Among patients treated with it, 34% died; the mortality rate improved if the drug was administered soon after infection, in a timely diagnosis – critical for those infected with diseases like Ebola that can cause sepsis and, eventually, multiple organ dysfunction syndrome, more quickly than other diseases. [22]
The drug is composed of three monoclonal antibodies (mAbs), initially harvested from mice exposed to Ebola virus proteins, that have been chimerized with human constant regions. [6] The components are chimeric monoclonal antibody c13C6 from a previously existing antibody cocktail called "MB-003" and two chimeric mAbs from a different antibody ...
This article covers the timeline of the 2014 Ebola virus epidemic in West Africa and its outbreaks elsewhere. [1] Flag icons denote the first announcements of confirmed cases by the respective nation-states, their first deaths, and their first secondary transmissions, as well as relevant sessions and announcements of agencies such as the World Health Organization (WHO), the U.S. Centers for ...