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The use of florfenicol in horses, and likely in other equids, typically causes diarrhea. This has been anecdotally reported to progress to lethal cases of acute colitis. Therefore, use of this antimicrobial in the equine patient should be limited to cases in which other, safer, options are not available. [6]
The use of antibiotics may also be associated with some forms of colitis-X. [11] In humans, C. difficile is the most serious cause of antibiotic-associated diarrhea, often a result of eradication of the normal gut flora by antibiotics. [12] In one equine study, colitis was induced after pretreatment with clindamycin and lincomycin, followed by ...
Oral administration can result in diarrhoea and gastrointestinal disturbance. This is particularly true of horses, such that it can be fatal. [9] Tylosin also has a foul taste that is difficult to disguise. The injectable formulations of tylosin can cause pain, inflammation, and itchiness around the injection site. [citation needed]
methimazole – used in treatment of hyperthyroidism; methocarbamol - muscle relaxant used to reduce muscle spasms associated with inflammation, injury, intervertebral disc disease, and certain toxicities; metoclopramide – potent antiemetic, secondarily as a prokinetic; metronidazole – antibiotic against anaerobic bacteria
Horses may display acute or chronic intermittent colic, peripheral edema secondary to protein losing enteropathy, decreased appetite, and diarrhea. Treatment involves decreasing the fiber levels of the horse's diet by reducing grass and hay, and placing the horse on an easily digestible pelleted feed until the colon can heal.
Clostridioides difficile, also known more commonly as C. diff, accounts for 10 to 20% of antibiotic-associated diarrhea cases, because the antibiotics administered for the treatment of certain disease processes such as inflammatory colitis also inadvertently kill a large portion of the gut flora, the normal flora that is usually present within the bowel.
A CDC infographic on how antibiotic-resistant bacteria have the potential to spread from farm animals. The use of antibiotics in the husbandry of livestock includes treatment when ill (therapeutic), treatment of a group of animals when at least one is diagnosed with clinical infection (metaphylaxis [1]), and preventative treatment (prophylaxis).
Destruction of the normal protective flora of beneficial bacteria can occur in dogs and horses. [21] [22] Dogs may have side effects that include: joint pain, loss of appetite, vomiting, flatulence (intestinal gas), fungal infections and digestive problems. [23] Like humans, dogs can have a similar side effect related to developing a serious ...
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