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Staphylococcus epidermidis is a Gram-positive bacterium, and one of over 40 species belonging to the genus Staphylococcus. [1] It is part of the normal human microbiota, typically the skin microbiota, and less commonly the mucosal microbiota and also found in marine sponges.
Current treatment includes topical and systemic antibacterial drugs which result in decreased C. acnes colonisation and/or activity. [41] Potential probiotic treatment includes the use of Staphylococcus epidermidis to inhibit C. acnes growth. S. epidermidis produces succinic acid which has been shown to inhibit C. acnes growth. [42]
The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermal layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.
Cefotaxime is an antibiotic used to treat several bacterial infections in humans, other animals, and plant tissue culture. [3] Specifically in humans it is used to treat joint infections, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, sepsis, gonorrhea, and cellulitis. [3]
It is primarily a pathogen for domestic animals, [3] [4] but has been known to affect humans as well. [5] S. pseudintermedius is an opportunistic pathogen that secretes immune-modulating virulence factors, has many adhesion factors, and the potential to create biofilms , all of which help to determine the pathogenicity of the bacterium.
Hepcidin is a protein that in humans is encoded by the HAMP gene. Hepcidin is a key regulator of the entry of iron into the circulation in mammals. [6]During conditions in which the hepcidin level is abnormally high, such as inflammation, serum iron falls due to iron trapping within macrophages and liver cells and decreased gut iron absorption.
Staphylococcus capitis is a coagulase-negative species (CoNS) of Staphylococcus.It is part of the normal flora of the skin of the human scalp, face, neck, scrotum, and ears and has been associated with prosthetic valve endocarditis, but is rarely associated with native valve infection.
Imiquimod has also been tested for treatment of vulvar intraepithelial neoplasia, [30] vaginal intraepithelial neoplasia, [31] common warts (a 2012 Cochrane review found no randomized controlled trials), [32] plantar warts, [33] warts in people with suppressed immune systems, [34] flat warts on face and neck, [33] and warts under and around ...