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An epinephrine autoinjector (or adrenaline autoinjector, also known by the trademark EpiPen) is a medical device for injecting a measured dose or doses of epinephrine (adrenaline) by means of autoinjector technology. It is most often used for the treatment of anaphylaxis. The first epinephrine autoinjector was brought to market in 1983.
[14] [15] Epinephrine does this through its effects on alpha and beta receptors. [15] It is found in many animals and some single-celled organisms, [16] [17] but the medication is produced synthetically and is not harvested from animals. [18] Jōkichi Takamine first isolated epinephrine in 1901, and it came into medical use in 1905.
The U.S. Food and Drug Administration (FDA) requires autoinjector expiration dates to ensure that the devices never contain less than 90% of the original dose of epinephrine, the study team notes.
Bupivicaine HCl 0.5% + epinephrine 1:200,000 gives a long duration of action of pulpal anaesthesia at more than 90 minutes. [3] Multiple factors affect the depth and duration of local anaesthetics' action.
Adrenaline, also known as epinephrine, is a hormone and medication [10] [11] which is involved in regulating visceral functions (e.g., respiration). [ 10 ] [ 12 ] It appears as a white microcrystalline granule. [ 13 ]
Learn about the problem of gun violence in America through these graphs and charts. The post Gun Violence Statistics in the United States: 12 Charts You Need to See appeared first on Reader's Digest.
Ephedrine, one of the most well-known selective NRAs.. A norepinephrine releasing agent (NRA), also known as an adrenergic releasing agent, is a catecholaminergic type of drug that induces the release of norepinephrine (noradrenaline) and epinephrine (adrenaline) from the pre-synaptic neuron into the synapse.
Norepinephrine is synthesized by the body from the amino acid tyrosine, [3] and is used in the synthesis of epinephrine, which is a stimulating neurotransmitter of the central nervous system. [4] All sympathomimetic amines fall into the larger group of stimulants (see psychoactive drug chart).