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Ashwagandha can impact thyroid hormones and immune function, so checking with a health care provider first is always wise, especially if you have underlying health concerns.”
A 2021 systematic review of prior studies on ashwagandha and stress found that subjects who took the supplement for six to eight weeks had lower cortisol levels compared to the placebo group.
A 2021 research review of both human and animal studies which suggests that Ashwagandha could be a helpful tool in managing depression, anxiety, insomnia and other mental health-related issues.
Zinc may increase free T 3 levels. [100] A small pilot study found Ashwagandha Root may increase T 3 and T4 levels, however, there's a lack of strong evidence of this benefit and Ashwagandha has a potential to cause adrenal insufficiency. [100]
Withania somnifera, known commonly as ashwagandha, [2] [3] [4] is an evergreen shrub in the Solanaceae or nightshade family that grows in Nepal, India, the Middle East, and parts of Africa. Several other species in the genus Withania are morphologically similar.
After long-term heavy strain, levels of thyroid hormones decrease. [2] This is exacerbated by other stressors such as undernutrition and lack of sleep , such as in a military training setting. During endurance exercise, before exhaustion, elevated thyroid hormone levels may happen due to increased expected energy demand (type 2 allostatic load).
Ashwagandha accomplishes this by lowering cortisol levels. Cortisol is the hormone that adrenal glands produce in response to stress . When these levels go down, we experience less stress.
The onset of TM requires toxic levels of the thyroxine hormone due to overproduction by the thyroid gland. Documented cases have only been diagnosed in conjunction with patients with hyperthyroidism. While hyperthyroidism is more common in women, the development of TM was more common among men with hyperthyroidism.
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