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Horse ointment, known as horse oil and horse fat, is a topical formulation derived from subcutaneous fat of horses. [1] Due to its thickness and viscosity , horse ointment is intended for topical use on human skin and mucous membranes to moisturize and increase the restoration of damaged skin.
Octreotate or octreotide acid is a somatostatin analogue that is closely related to octreotide. Its amino acid sequence is H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-OH while octreotide has the terminal threonine reduced to the corresponding amino alcohol.
Octreotide is used for the treatment of growth hormone producing tumors (acromegaly and gigantism), when surgery is contraindicated, pituitary tumors that secrete thyroid-stimulating hormone (thyrotropinoma), [citation needed] diarrhea and flushing episodes associated with carcinoid syndrome, and diarrhea in people with vasoactive intestinal peptide-secreting tumors ().
The combination of the beta emitter 177 Lu with DOTA-TATE can be used in the treatment of cancers expressing the relevant somatostatin receptors. [16] The U.S. Food and Drug Administration (FDA) considers 177 Lu-dotatate to be a first-in-class medication. [17] Alternatives to 177 Lu-DOTA-TATE include 90 Y (T 1/2 = 64.6 h) DOTA-TATE.
As somatostatin can cause inhibition of hormone production that uses it as a mediating hormone, it has an antiproliferative effect on cell tumors, especially in neuroendocrine tumors. [2] Somatostatin analogue therapy uses longer-acting agonists than the endogenous somatostatin to extend the antiproliferative effects. [24]
The sternum and ileum contain the same quality of stem cells, but the ileum is usually harder to use in horses older than 5 years of age, because the marrow cavity shrinks. Marrow is collected using a Jamshidi needle in a sedated horse. Unlike people, horses usually tolerate the procedure well, with little pain.
References A ace Slang for the drug acepromazine or acetyl promazine (trade names Atravet or Acezine), which is a sedative : 3 commonly used on horses during veterinary treatment, but also illegal in the show ring. Also abbreviated ACP. action The way a horse elevates its legs, knees, hock, and feet. : 3 Also includes how the horse uses its shoulder, humerus, elbow, and stifle; most often used ...
Lanreotide, sold under the brand name Somatuline among others, is a medication used in the management of acromegaly and symptoms caused by neuroendocrine tumors, most notably carcinoid syndrome. It is a long-acting analogue of somatostatin, like octreotide. Lanreotide (as lanreotide acetate) is manufactured by Ipsen.