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In the ‘80s, researchers set out to test a medication called sildenafil citrate for treating high blood pressure and angina (chest pain) from heart disease.
Sildenafil (compound UK-92,480) was synthesized by a group of pharmaceutical chemists led by Simon Campbell [55] working at Pfizer's Sandwich, Kent, research facility in England. It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a symptom of ischaemic heart disease). [56]
Heart Disease One of the most common forms of heart failure happens when the left heart ventricle (responsible for pumping oxygen-rich blood to the rest of the body) can’t effectively do its job.
Sildenafil, the active ingredient in Viagra, is actually used to treat a certain kind of high blood pressure in the lungs. Called Revatio (and also available as generic Revatio), this version of ...
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
How to Use Viagra for Best Results. Viagra is great as an ED treatment, but taking it in particular conditions can make it even more effective. To get the best results from Viagra when treating ...
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