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Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depression, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11]
As mentioned previously, sertraline can also cause you to be more sleepy than usual. ... with a 2017 study from Australia finding that high-dosage antidepressant users gain 0.28kg (about 0.6 lbs ...
Which drugs you currently and how high the dose is. ... Zoloft (sertraline) and Lexapro (escitalopram). Effectiveness and side effect rates can vary between SSRIs. As such, your healthcare ...
[187] [188] High occupancy of the σ 1 receptor by clinical dosages of fluvoxamine has been observed in the human brain in positron emission tomography (PET) research. [ 187 ] [ 188 ] It is thought that agonism of the σ 1 receptor by fluvoxamine may have beneficial effects on cognition .
Serotonin reuptake inhibitors (SSRI) have been associated with a state of restlessness, lability, agitation, and anxiety termed "activation syndrome". In some people, this state change can increase suicidal tendencies, especially in those under age 25 and during the initial weeks of treatment. [2]
Sertraline (Zoloft) As an SSRI antidepressant, escitalopram is commonly prescribed to treat depression. The FDA also approves it for the treatment of generalized anxiety disorder (GAD).
This can be estimated to result in a free concentration of 3.75 ng/mL (12.2 nM), which is still only about half of the K i of sertraline for the DAT. [8] As such, it seems unlikely that sertraline would produce much inhibition of dopamine reuptake even at clinically used dosages well in excess of the recommended maximum clinical dosage. [11]
Sertraline. Sold under the brand ... especially if you’ve been taking one at a high dose for a while. If you’re prescribed any type of benzodiazepine, do not abruptly stop taking it without ...