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This list of protein subcellular localisation prediction tools includes software, databases, and web services that are used for protein subcellular localization prediction. Some tools are included that are commonly used to infer location through predicted structural properties, such as signal peptide or transmembrane helices , and these tools ...
In immunology, epitope mapping is the process of experimentally identifying the binding site, or epitope, of an antibody on its target antigen (usually, on a protein). [ 1 ] [ 2 ] [ 3 ] Identification and characterization of antibody binding sites aid in the discovery and development of new therapeutics , vaccines , and diagnostics .
The part of the antigen that immunoglobulin or antibodies bind to is called a B-cell epitope. [11] B cell epitopes can be divided into two groups: conformational or linear. [11] B cell epitopes are mainly conformational. [12] [13] There are additional epitope types when the quaternary structure is considered. [13]
E-Cell [68] One of the earliest attempts at a whole-cell modeling platform. C/C++: No: 1999 Gepasi [69] First GUI application that supported metabolic control analysis and parameter estimation. C/C++: Yes: 1993 Jarnac [70] First GUI based application to support scripting in systems biology modeling. Object Pascal: Yes: 2000 JSim [71]
HSE is used in predicting discontinuous B-cell epitopes. [2] Song et al. have developed an online webserver termed HSEpred to predict half-sphere exposure from protein primary sequences. [ 3 ] HSEpred server can achieve the correlation coefficients of 0.72 and 0.68 between the predicted and observed HSE-up and HSE-down measures, respectively ...
Link alignment results to analysis tools (Primer design, Gel mobility and Maps, Plasmapper, siRNA design Epitope prediction), Save research logs, Create custom toolbars Accession number, GI number, PDB ID, FASTA , drag-drop from external URL from within the user interface
Neural network promoter prediction: Prokaryotes, Eukaryotes [38] NNSPLICE: Neural network splice site prediction: Drosophila, Human [39] ORFfinder: Graphical analysis tool to find all open reading frames: Prokaryotes, Eukaryotes [40] Regulatory Sequence Analysis Tools: Series of modular computer programs to detect regulatory signals in non ...
In academia, computational immunology is a field of science that encompasses high-throughput genomic and bioinformatics approaches to immunology.The field's main aim is to convert immunological data into computational problems, solve these problems using mathematical and computational approaches and then convert these results into immunologically meaningful interpretations.