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  2. Teriflunomide - Wikipedia

    en.wikipedia.org/wiki/Teriflunomide

    Teriflunomide inhibits rapidly dividing cells, including activated T cells, which are thought to drive the disease process in MS. Teriflunomide may decrease the risk of infections compared to chemotherapy-like drugs because of its more-limited effects on the immune system.

  3. Casimersen - Wikipedia

    en.wikipedia.org/wiki/Casimersen

    Casimersen was approved for medical use in the United States in February 2021, [1] [2] [6] and it is the first FDA-approved targeted treatment for people who have a confirmed mutation of the DMD gene that is amenable to skipping exon 45. [2]

  4. Seladelpar - Wikipedia

    en.wikipedia.org/wiki/Seladelpar

    Seladelpar was approved for medical use in the United States in August 2024. [5] The FDA granted the application breakthrough therapy designation. [8]In December 2024, the Committee for Medicinal Products for Human Use of the European Medicines Agency (EMA) adopted a positive opinion, recommending the granting of a conditional marketing authorization for the medicinal product Seladelpar Gilead ...

  5. Disruptive mood dysregulation disorder - Wikipedia

    en.wikipedia.org/wiki/Disruptive_mood...

    Disruptive mood dysregulation disorder (DMDD) is a mental disorder in children and adolescents characterized by a persistently irritable or angry mood and frequent temper outbursts that are disproportionate to the situation and significantly more severe than the typical reaction of same-aged peers.

  6. Tolrestat - Wikipedia

    en.wikipedia.org/wiki/Tolrestat

    Tolrestat (AY-27773) is an aldose reductase inhibitor [1] which was approved for the control of certain diabetic complications. [2]While it was approved for marketed in several countries, it failed a Phase III trial in the U.S. due to toxicity and never received FDA approval.

  7. Afamitresgene autoleucel - Wikipedia

    en.wikipedia.org/wiki/Afamitresgene_autoleucel

    Afamitresgene autoleucel is a melanoma-associated antigen A4 (MAGE-A4)-directed genetically modified autologous T cell immunotherapy indicated for the treatment of adults with unresectable or metastatic synovial sarcoma who have received prior chemotherapy, are HLA-A*02:01P, -A*02:02P, -A*02:03P, or -A*02:06P positive and whose tumor expresses the MAGE-A4 antigen as determined by FDA-approved ...

  8. Which Medications Are FDA-Approved for Weight Loss? - AOL

    www.aol.com/lifestyle/medications-fda-approved...

    There are seven FDA-approved weight loss medications currently available. These medications are safe and effective and have minimal side effects.

  9. Trifluridine/tipiracil - Wikipedia

    en.wikipedia.org/wiki/Trifluridine/tipiracil

    Trifluridine/tipiracil (FTD–TPI), sold under the brand name Lonsurf, is a fixed-dose combination medication that is used as a third- or fourth-line treatment of metastatic colorectal cancer or gastric cancer, after chemotherapy and targeted therapeutics have failed.

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