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A coronary stent is a tube-shaped device placed in the coronary arteries that supply blood to the heart, to keep the arteries open in patients suffering from coronary heart disease. The vast majority of stents used in modern interventional cardiology are drug-eluting stents (DES). They are used in a medical procedure called percutaneous ...
Paclitaxel is used as an antiproliferative agent for the prevention of restenosis (recurrent narrowing) of coronary and peripheral stents; locally delivered to the wall of the artery, a paclitaxel coating limits the growth of neointima (scar tissue) within stents. [23] Paclitaxel drug-eluting stents for coronary artery placement are sold under ...
The paclitaxel-eluting Taxus stent received FDA approval and was launched in the US in 2004, [145] after a series of trials that compared it with a bare metal stent in various settings. The trials showed a significant reduction in target lesion revascularization and major adverse cardiac events with the Taxus stent at 9 and 12 months.
The first two drug-eluting stents to be utilized were the paclitaxel-eluting stent and the sirolimus-eluting stent, both of which have received approval from the U.S. Food and Drug Administration. Most current FDA-approved drug-eluting stents use sirolimus (also known as rapamycin), everolimus and zotarolimus.
Stents have been with us for about 20 years now, and they have definitely made a significant impact in both the treatment of coronary artery disease and the med-tech landscape. As the leaders in ...
Daljeet Singh Gambhir is an Indian cardiologist, medical academic, researcher and inventor and the Group Director of Cardiology at Kailash Group of Hospitals and Heart Institute, Noida. [1] He is the inventor of Infinnium Paclitaxel-Eluting Stent , a reportedly cheaper drug-eluting stent which he first presented at the EuroPCR meeting held in ...
A coronary angioplasty is a therapeutic procedure to treat the stenotic (narrowed) coronary arteries of the heart found in coronary heart disease. [1] These stenotic segments of the coronary arteries arise due to the buildup of cholesterol -laden plaques that form in a condition known as atherosclerosis . [ 3 ]
A dual therapy stent is a coronary artery stent that combines the technology of an antibody-coated stent and a drug-eluting stent. [1] Currently, second-generation drug-eluting stents require long-term use of dual-antiplatelet therapy , which increases the risk of major bleeding occurrences in patients. [ 2 ]
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