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1000 Genomes Project: launched in January 2008. The genomes of more than a thousand anonymous participants from a number of different ethnic groups were analyzed and made publicly available. EggNOG Database: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses. It provides ...
Whole genomes. This level contains information about the virus species or isolate and its entire genomic sequence. Annotated genes. This level contains all the predicted ORFs (open reading frames) in a particular virus genome, together with their DNA and (translated) protein sequences. Ortholog groups (families).
Some viruses may have only replicase gene and use capsid gene of other e.g. endogenous virus. Most viral genomes are 10-100kb, whereas bacteriophages tend to have larger genomes carrying parts of genome translation machinery genes from their host. In contrast, RNA viruses have smaller genomes, with maximum 35kb by coronavirus.
The viruses have large, double-stranded DNA genomes (300 to >1000 kilobasepairs) that encode a large contingent of genes (of the order of 1000 genes). [ 3 ] [ 5 ] The best characterized giant viruses are the phylogenetically related mimivirus and megavirus , which belong to the family Mimiviridae (aka Megaviridae ), and are distinguished by ...
The 1000 Genomes Project (1KGP), taken place from January 2008 to 2015, was an international research effort to establish the most detailed catalogue of human genetic variation at the time. Scientists planned to sequence the genomes of at least one thousand anonymous healthy participants from a number of different ethnic groups within the ...
The Marseilleviridae viruses have double stranded DNA genomes that are about 368 kilobases long. Members of the family can have about 457 open reading frames (ORFs) in its genome. The host organisms are amoebae. Once it infects, viral replication takes place in virus factories in the cytoplasm.
[1] [3] Sequencing viruses can be challenging because viruses lack a universally conserved marker gene so gene-based approaches are limited. [3] [4] Metagenomics can be used to study and analyze unculturable viruses and has been an important tool in understanding viral diversity and abundance and in the discovery of novel viruses.
The EsV-1 phaeovirus is an exception with 231 protein encoding genes, which means it has one gene per approximately 1450 bp. In spite of the compact genomes typically found in viruses, Phycodnaviridae genomes have repetitive regions usually near the terminal ends and certain tandem repeats located throughout the genome. It is suggested that ...