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The genome organisation of HBV. Some genes overlap. (ORF Core, at bottom left, encodes HBcAg. HBcAg (core antigen) is a hepatitis B viral protein. [1] [2] It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious).
The icosahedral core particle is made of 180 or 240 copies of the core protein, alternatively known as hepatitis B core antigen, or HBcAg. During this 'window' in which the host remains infected but is successfully clearing the virus, IgM antibodies specific to the hepatitis B core antigen (anti-HBc IgM) may be the only serological evidence of ...
The structure of hepatitis B virus. Hepatitis B virus is a member of the Hepadnavirus family. [11] The virus particle, called Dane particle [12] (), consists of an outer lipid envelope and an icosahedral nucleocapsid core composed of protein.
(ORF Core, at bottom left, encodes HBcAg; when translated together with Pre C, it produces soluble HBeAg.) HBeAg is a hepatitis B viral protein , produced by the HBcAg reading frame. It is an indicator of active viral replication ; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the ...
It was shown to be associated with "serum hepatitis" by A. M. Prince in 1968. [7] The outer membrane of the virion is sometimes extended as a tubular tail on one side of the virus particle (not shown); [2] [3] these virion "tails" are identical to the small particles. [2] [3] The hepatitis B e antigens (shown) are considered not part of the ...
The structure of the Hepatitis B virus as first described by Dane & al. [1] and Jokelainen, Krohn & al. [2] during 1970. The hepatitis B virion is a complex, double shelled, spherical particle with a 42 nm diameter. [1] [2] [3] The 6 nm [2] thick outer viral envelope or membrane contains host-derived lipids and surface proteins, [2] known ...
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Hepatitis D is a defective virus that requires hepatitis B to replicate and is only found with hepatitis B co-infection. [17] In adults, hepatitis B infection is most commonly self-limiting, with less than 5% progressing to chronic state, and 20 to 30% of those chronically infected developing cirrhosis or liver cancer. [ 30 ]