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Structural model at atomic resolution of bacteriophage T4 [1] The structure of a typical myovirus bacteriophage Anatomy and infection cycle of bacteriophage T4. A bacteriophage (/ b æ k ˈ t ɪər i oʊ f eɪ dʒ /), also known informally as a phage (/ ˈ f eɪ dʒ /), is a virus that infects and replicates within bacteria and archaea.
In molecular biology, bacteriophage scaffolding proteins are proteins involved in bacteriophage assembly. The assembly of a macromolecular structure proceeds via a specific pathway of ordered events and involves conformational changes in the proteins as they join the assembly.
The prokaryotic cell is shown with its DNA, in green. 2. The bacteriophage attaches and releases its DNA, shown in red, into the prokaryotic cell. 3. The phage DNA then moves through the cell to the host's DNA. 4. The phage DNA integrates itself into the host cell's DNA, creating prophage. 5. The prophage then remains dormant until the host ...
The structure of a typical bacteriophage. Bacteriophages are viruses that infect bacteria and archaea. [76] They are important in marine ecology: as the infected bacteria burst, carbon compounds are released back into the environment, which stimulates fresh organic growth. Bacteriophages are useful in scientific research because they are ...
Schematic drawing of a Φ29 phage virion (cross section and side view). The structure of Φ29 is composed of seven main proteins: the terminal protein (p3), the head or capsid protein (p8), the head or capsid fiber protein (p8.5), the distal tail knob (p9), the portal or connector protein (p10), the tail tube or lower collar proteins (p11), and the tail fibers or appendage proteins (p12*).
The lytic cycle, the reproductive cycle of the bacteriophage, has six stages: → attachment: the phage attaches itself to the surface of the host cell → penetration: the phage injects its DNA through the cell membrane → transcription: the host cell's DNA is degraded and the cell's metabolism is directed to initiate phage biosynthesis
The history of phage study is captured, in part, in the books published on the topic. This is a list of over 100 monographs on or related to phages. List of phage monographs (descending date order)
However, some tailed bacteriophage genomes can vary quite significantly in nucleotide sequence, even among the same genus. Due to their characteristic structure and possession of potentially homologous genes, it is believed these bacteriophages possess a common origin.