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The minimum dose (5 mg/kg) was confirmed in a clinical trial performed by HTI Bio-services, Inc. [5] It evaluated the effective dose for the treatment of an infected dermal wound. The study included forty-eight mixed breed dogs (both male and female) with weights ranging from 14.5-24.5 kilograms. These dogs were randomly placed into treatment ...
Sulfasalazine was approved for medical use in the United States in 1950. [5] It is on the World Health Organization's List of Essential Medicines. [8] Sulfasalazine is available as a generic medication. [5] In 2020, it was the 284th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [9] [10]
pimobendan – phosphodiesterase 3 inhibitor used to manage heart failure in dogs; pirlimycin – antimicrobial; ponazuril – anticoccidial; praziquantel – treatment of infestations of the tapeworms Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus; prazosin – sympatholytic used in hypertension and abnormal muscle contractions
Failing to report an adverse reaction is fairly standard in human medicine (2) and is probably an even more common problem in veterinary medicine. Now that over 40,000 adverse reactions have been ...
An aminosalicylate is a class of medications that is often used to treat ulcerative colitis [1] and Crohn's disease. The class includes among others: [1] 4-Aminosalicylic acid; Balsalazide; Olsalazine; Sulfasalazine; Mesalazine (5-Aminosalicylic acid) Side effects may include abdominal pain, diarrhea, headaches, and nausea. [1]
Oral anti-inflammatory drugs require four to six weeks to work. Once remission is induced, maintenance levels can be used: sulfasalazine 2 g/day, mesalamine 1.2-2.4 g/day, or olsalazine 1 g/day. Patients on high dose sulfasalazine require folic supplementation (1 mg/day) because it inhibits folate absorption.
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