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Zinc pyrithione (or pyrithione zinc) is a coordination complex of zinc. It has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis [ 2 ] and dandruff .
Pyrithione is the common name of an organosulfur compound with molecular formula C 5 H 5 NOS, chosen as an abbreviation of pyridinethione, and found in the Persian shallot. [4] It exists as a pair of tautomers, the major form being the thione 1-hydroxy-2(1H)-pyridinethione and the minor form being the thiol 2-mercaptopyridine N-oxide; it crystallises in the thione form. [5]
Structure of zinc pyrithione, a popular antidandruff medicine. Zinc pyrithione is a coordination complex of a sulfur-substituted pyridine-N-oxide. This zinc complex has useful fungistatic and bacteriostatic properties.. [5]
Like selenium sulfide, zinc pyrithione (a zinc complex with two chelating pyrithione anions) also reduces epidermal turnover and inhibits fungal growth. [3] [unreliable medical source?] It is often administered with ketoconazole for better results. The symptoms do not resolve completely even after prolonged medication.
1) Zinc pyrithione is a coordination complex of zinc salt and pyrithione salt. 2) As mentioned in the body of text, zinc pyrithione has been applied in shampoo for many years. This information should be included in the leading section. 3) The emphasis of the use of zinc pyrithione in seborrheic dermatitis is not appropriate.
Zinc pyrithione This page was last edited on 3 December 2021, at 18:01 (UTC). Text is available under the Creative Commons Attribution ...
Zinc oxide, ZnO, is the most important manufactured compound of zinc, with a wide variety of uses. [2] It crystallizes with the Wurtzite structure. It is amphoteric , dissolving in acids to give the aqueous Zn 2+ ion and in alkali to give the zincate (a.k.a. tetrahydroxozincate) ion, [Zn(OH) 4 ] 2− .
Zinc is an inexpensive and effective part of treatment of diarrhea among children in the developing world. Zinc becomes depleted in the body during diarrhea and replenishing zinc with a 10- to 14-day course of treatment can reduce the duration and severity of diarrheal episodes and may also prevent future episodes for as long as three months. [175]
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