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Trabecular edema, also known as bone marrow edema (BME), is a traditional term describing the interstitial fluid accumulation at the trabecular bone marrow.The term was first used in 1988, [1] referring to the changes in the bone marrow due to inflammation. [3]
There is a bone marrow fragment in the middle, and multiple single hematopoietic cells in the blood, being evidence of fracture as the source of the embolism. Once fat emboli enter the blood circulation, they can lodge at various sites of the body, most commonly in the lungs (up to 75% of cases).
Normal bone contains internal scaffolding, called trabeculae. Red bone marrow , which produces blood cells , is located in the hollows between the trabeculae. Modic changes Type 1 reflects oedema adjacent to the disc, fissured endplates, microfractures of the trabeculae, granular tissue, high levels of immunoreactive nerve fibers, and TNF alpha ...
Excessive systemic accumulations of hemosiderin may occur in macrophages in the liver, lungs, spleen, kidneys, lymph nodes, and bone marrow. These accumulations may be caused by excessive red blood cell destruction (haemolysis), excessive iron uptake/hyperferraemia, or decreased iron utilization (e.g., anaemia of copper toxicity) uptake ...
Bone marrow failure in both children and adults can be either inherited or acquired. Inherited bone marrow failure is often the cause in young children, while older children and adults may acquire the disease later in life. [3] Acquired bone marrow failure may be due to aplastic anemia [4] or myelodysplastic syndrome.
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Normally, bone continuously breaks down and rebuilds—old bone is resorbed and replaced with new bone. The process keeps the skeleton strong and helps it to maintain a balance of minerals. [ 23 ] In the course of avascular necrosis, however, the healing process is usually ineffective and the bone tissues break down faster than the body can ...
Alcatraz Prison. San Francisco Located on an island in San Francisco Bay, Alcatraz was a maximum-security prison from 1934 until 1963, holding some of the country's most notorious and dangerous ...