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In bioinformatics and biochemistry, the FASTA format is a text-based format for representing either nucleotide sequences or amino acid (protein) sequences, in which nucleotides or amino acids are represented using single-letter codes. The format allows for sequence names and comments to precede the sequences.
FASTA is a DNA and protein sequence alignment software package first described by David J. Lipman and William R. Pearson in 1985. [1] Its legacy is the FASTA format which is now ubiquitous in bioinformatics .
UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects.It contains a large amount of information about the biological function of proteins derived from the research literature.
FASTQ format is a text-based format for storing both a biological sequence (usually nucleotide sequence) and its corresponding quality scores. Both the sequence letter and quality score are each encoded with a single ASCII character for brevity.
fasta.bioch.virginia.edu /wrpearson William Raymond Pearson is professor of biochemistry and molecular Genetics in the School of Medicine [ 3 ] [ 9 ] at the University of Virginia . [ 10 ] [ 11 ] [ 12 ] Pearson is best known for the development of the FASTA format.
Biological sequence formats are a collection of file formats that are used in the biomedical sciences. There are a number of these. Most of these formats were developed for use in particular programmes and have subsequently been reused by other programmes.
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The first two are a natural consequence of most representations of alignments and their annotation being human-unreadable and best portrayed in the familiar sequence row and alignment column format, of which examples are widespread in the literature.