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Motile cilia are found in large numbers on respiratory epithelial cells – around 200 cilia per cell, where they function in mucociliary clearance, and also have mechanosensory and chemosensory functions. [12] [13] [14] Motile cilia on ependymal cells move the cerebrospinal fluid through the ventricular system of the brain.
This type of cilia is found in the sperm of human and other mammals. Secondary cytosolic cilia are formed in parallels to the formation of the typical compartmentalized cilium. One end of the axoneme is exposed to the cytoplasm as the other end of the axoneme is formed as compartmentalized cilia. This type of cilia is found in insects. Tertiary ...
Primary cilia are common organelles found in eukaryotic cells; they play an important role in development of animals. Drosophila have unique properties in their spermatocyte primary cilia—they are assembled by four centrioles independently in the G2 phase and are sensitive to microtubule-targeting drugs. Normally, primary cilia will develop ...
Cilia Structure. Primary cilia are found to be formed when a cell exits the cell cycle. [2] Cilia consist of four main compartments: the basal body at the base, the transition zone, the axenome which is an arrangement of nine doublet microtubules and considered to be the core of the cilium, and the ciliary membrane. [2]
[1] [2] Cilia and flagella are found on many cells, organisms, and microorganisms, to provide motility. The axoneme serves as the "skeleton" of these organelles, both giving support to the structure and, in some cases, the ability to bend. Though distinctions of function and length may be made between cilia and flagella, the internal structure ...
Sperm cells cannot divide and have a limited lifespan, but after fusion with egg cells during fertilization, a new organism begins developing, starting as a totipotent zygote. The human sperm cell is haploid, so that its 23 chromosomes can join the 23 chromosomes of the female egg to form a diploid cell with 46 paired chromosomes.
The tail of the sperm - the flagellum - confers motility upon the sperm, and has three principal components: a central skeleton constructed of 11 microtubules collectively termed the axoneme and similar to the equivalent structure found in cilia; a thin cell membrane covering the axoneme
SPEF2 is expressed in all ciliated cells and is required for cilia function. [ 9 ] [ 10 ] Sperm contain cilia, and a mutation in the SPEF2 gene can cause male infertility due to immobile sperm . [ 9 ] [ 10 ] In a pig animal model, a SPEF2 mutation affects the sperm tail development. [ 10 ]