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Mohs surgery is the gold standard method for obtaining complete margin control during removal of a skin cancer (complete circumferential peripheral and deep margin assessment - CCPDMA) using frozen section histology. [1] CCPDMA or Mohs surgery allows for the removal of a skin cancer with very narrow surgical margin and a high cure rate.
Skin biopsy is a biopsy technique in which a skin lesion is removed to be sent to a pathologist to render a microscopic diagnosis.It is usually done under local anesthetic in a physician's office, and results are often available in 4 to 10 days.
Comparing Mohs Surgery Method to smashing an aluminum pie pan How a Mohs Section is flattened with relaxing incisions False negative in standard bread loafing histology: If the pathologist looks only at the margin of the three narrow slices, the many cancerous cells on the discarded margins will be missed.
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The American College of Mohs Surgery (abbreviated as ACMS) is a membership-based organization of surgeons who are fellowship-trained (FACMS) in Mohs surgery, a technique that removes skin cancer in stages, one tissue layer at a time. The ACMS is the oldest and largest professional membership organization for Mohs surgeons.
There are two major types of specimens submitted for surgical pathology analysis: biopsies and surgical resections. [1]A biopsy is a small piece of tissue removed primarily for the purposes of surgical pathology analysis, most often in order to render a definitive diagnosis.
A 2009 meta-analysis of randomized controlled trials found a small difference in survival rates favoring wide excision of primary cutaneous melanomas, but these results were not statistically significant. [108] Mohs surgery has been reported with cure rate as low as 77% [109] and as high as 98.0% for melanoma-in-situ. [110]
The cure rate is highly user dependent. [5] The more aggressive the surgeon is at performing EDC, the higher the cure rate. Like standard excision, the wider the surgical margin, the higher the cure rate.