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  2. Lobular carcinoma in situ - Wikipedia

    en.wikipedia.org/wiki/Lobular_carcinoma_in_situ

    Like the cells of atypical lobular hyperplasia and invasive lobular carcinoma, the abnormal cells of LCIS consist of small cells with oval or round nuclei and small nucleoli detached from each other. [12] Mucin-containing signet-ring cells are commonly seen. LCIS generally leaves the underlying architecture intact and recognisable as lobules.

  3. Histopathology of colorectal adenocarcinoma - Wikipedia

    en.wikipedia.org/wiki/Histopathology_of...

    The most common form of colon cancer is adenocarcinoma, constituting between 95% [2] and 98% [3] of all cases of colorectal cancer. Other, rarer types include lymphoma, adenosquamous and squamous cell carcinoma. Some subtypes have been found to be more aggressive. [4]

  4. Colorectal adenoma - Wikipedia

    en.wikipedia.org/wiki/Colorectal_adenoma

    The colorectal adenoma is a benign glandular tumor of the colon and the rectum. It is a precursor lesion of the colorectal adenocarcinoma ( colon cancer ). [ 1 ] [ 2 ] [ 3 ] They often manifest as colorectal polyps .

  5. Adenoma - Wikipedia

    en.wikipedia.org/wiki/Adenoma

    For example, adenomatous polyps in the colon may be pedunculated (lobular head with a long slender stalk) or sessile (broad base). The adenomatous proliferation is characterized by different degrees of cell dysplasia ( atypia or loss of normal differentiation of epithelium) irregular cells with hyperchromatic nuclei, stratified or ...

  6. Carcinoma in situ - Wikipedia

    en.wikipedia.org/wiki/Carcinoma_in_situ

    Exceptions include CIS of the colon (polyps), the bladder (preinvasive papillary cancer), or the breast (ductal carcinoma in situ or lobular carcinoma in situ). Many forms of CIS have a high probability of progression into cancer, [ 6 ] and therefore removal may be recommended; however, progression of CIS is known to be highly variable and not ...

  7. Familial adenomatous polyposis - Wikipedia

    en.wikipedia.org/wiki/Familial_adenomatous_polyposis

    The incidence of the mutation is between 1 in 10,000 and 1 in 15,000 births. By age 35 years, 95% of individuals with FAP (>100 adenomas) have polyps. Without colectomy, colon cancer is virtually inevitable. The mean age of colon cancer in untreated individuals is 39 years (range 34–43 years). [13]

  8. Precancerous condition - Wikipedia

    en.wikipedia.org/wiki/Precancerous_condition

    Premalignant lesions are morphologically atypical tissue which appear abnormal when viewed under the microscope, and which are more likely to progress to cancer than normal tissue. [7] Precancerous conditions and lesions affect a variety of organ systems, including the skin, oral cavity, stomach, colon, lung, and hematological system.

  9. Sessile serrated lesion - Wikipedia

    en.wikipedia.org/wiki/Sessile_serrated_lesion

    A sessile serrated lesion (SSL) is a premalignant flat (or sessile) lesion of the colon, predominantly seen in the cecum and ascending colon. SSLs are thought to lead to colorectal cancer through the (alternate) serrated pathway. [1] [2] This differs from most colorectal cancer, which arises from mutations starting with inactivation of the APC ...

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