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Dexmedetomidine, under the trade name Dexdomitor (Orion Corporation), was approved in the European Union for use in cats and dogs in 2002, for sedation and induction of general anesthesia. [49] The FDA approved dexmedetomidine for use in dogs in 2006 and cats in 2007.
The minimum lethal dose in dogs is over 5 mg/m 2; dogs have tolerated getting ten times the standard dose. [9] [33] Signs of overdose include panting, trembling, vomiting, and diarrhea, as well as increased blood levels of creatine kinase, aspartate transaminase, and alanine transaminase. Dogs who received atipamezole without first receiving ...
Medetomidine is a racemic mixture of two optical or stereoisomers, levomedetomidine and dexmedetomidine. [4] The latter causes the alpha 2- adrenergic agonist effects. [5] It is often used as the hydrochloride salt, medetomidine hydrochloride, a crystalline white solid that can be administered as an intravenous drug solution with sterile water.
Axl Rose has settled a lawsuit brought on by Sheila Kennedy accusing him of sexual assault. The Guns N' Roses rocker previously attempted to have the lawsuit, filed in November 2023, dismissed in ...
Additionally, acepromazine is used as a vasodilator in the treatment of laminitis, where an oral dose equivalent to "mild sedation" is commonly used, although the dose used is highly dependent on the treating veterinarian. While it is shown to elicit vasodilation in the distal limb, evidence showing its efficacy at increasing perfusion in the ...
A new study says that air pollution — specifically, the kind caused by car exhaust — may be a significant cause of rising rates of autism in children. Exposure to nitric oxide (NO)— which is ...
Katie Holmes has made herself at home in New York's Theater District while performing on Broadway — and she's been welcomed as a regular by a local Starbucks staff.. The actress, 45, appeared on ...
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
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