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  2. David A. Sinclair - Wikipedia

    en.wikipedia.org/wiki/David_A._Sinclair

    David Andrew Sinclair AO (born June 26, 1969) is an Australian-American biologist and academic known for his research on aging and epigenetics. Sinclair is a professor of genetics at Harvard Medical School and the founding director of the Paul F. Glenn Laboratories for the Biological Mechanisms of Aging at Harvard.

  3. Sirtris Pharmaceuticals - Wikipedia

    en.wikipedia.org/wiki/Sirtris_Pharmaceuticals

    Sirtris Pharmaceuticals, Inc. was a biotechnology company based in Cambridge, MA that developed therapies for type 2 diabetes, cancer, and other diseases. Conceived in 2004 by Harvard University biologist David Sinclair and Andrew Perlman, [1] and founded that year by Sinclair and Perlman, along with Christoph Westphal, Richard Aldrich, Richard Pops, and Paul Schimmel, [2] the company was ...

  4. One Little Pill - Wikipedia

    en.wikipedia.org/wiki/One_Little_Pill

    One Little Pill is a documentary film about the Sinclair method of treating alcohol abuse. [2] The film follows the lives of several people who have suffered from alcoholism, and have been helped by the treatment. Perspectives from scientists, treatment centers, doctors, and a legal prosecutor are also presented.

  5. OvaScience - Wikipedia

    en.wikipedia.org/wiki/OvaScience

    OvaScience was a publicly traded biotechnology company, focused on female infertility.It was founded in 2011 by Michelle Dipp, Richard Aldrich, Christoph Westphal, Jonathan Tilly, and David Sinclair and is based on scientific work done by Tilly concerning mammalian oogonial stem cells and work on mitochondria by Sinclair.

  6. Timeline of aging research - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_aging_research

    In January, a team led by David Sinclair shows in a 13-year-long international study how DNA breaks or epigenetic damage are a major driver of epigenetic change, and how the loss of epigenetic information is a cause of aging in mammals. It concluded that the loss of epigenetic information can drive aging independently of changes to the genetic ...

  7. John David Sinclair - Wikipedia

    en.wikipedia.org/wiki/John_David_Sinclair

    John David Sinclair (March 28, 1943 – April 6, 2015) was an American scientist and researcher best known for discovering the Alcohol Deprivation Effect (ADE) and targeted pharmacological extinction, otherwise known as the Sinclair Method, as a medication treatment for Alcohol Use Disorder (AUD).

  8. Lifespan: Why We Age – and Why We Don't Have To - Wikipedia

    en.wikipedia.org/wiki/Lifespan:_Why_We_Age...

    Lifespan debuted at #11 on The New York Times hardcover nonfiction bestseller list on September 28, 2019. [1]The book received mixed reviews from critics. "If you're even mildly hopeful about dunking a basketball at the age of 50, or hiking the Appalachian Trail at 70, or blowing 100 candles out on your birthday cake someday, you might consider making room for Lifespan on your bookshelf," one ...

  9. Talk:Sinclair method - Wikipedia

    en.wikipedia.org/wiki/Talk:Sinclair_method

    In 1969, the government owned Alko Labs - currently the National Public Health and Welfare Institute, Helsinki - recruited Dr. David Sinclair from the University of Oregon after his publications on the Alcohol Deprivation Effect [1] with the first human trials using naltrexone and nalmefene starting in the mid 1990s.