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Hypokalemic periodic paralysis (hypoKPP), also known as familial hypokalemic periodic paralysis (FHPP), [1] is a rare, autosomal dominant channelopathy characterized by muscle weakness or paralysis when there is a fall in potassium levels in the blood (hypokalemia).
Hypokalemia is a low level of potassium (K +) in the blood serum. [1] Mild low potassium does not typically cause symptoms. [ 3 ] Symptoms may include feeling tired , leg cramps , weakness , and constipation . [ 1 ]
This disease is encountered typically after the 1st decade of life, i.e., during adolescence or adulthood. However, it can occur in the neonatal period. Heterozygous carriers of the SLC12A3 gene mutations are 1% of the population. [16] A person with Gitelman syndrome has a low probability of passing the disease to their offspring.
Another agency, the Thoroughbred Retirement Foundation hosts hundreds of horses over 15 farms. The Unbridled Sanctuary, named for the 1990 Derby winner, hosts retirees in New York.
"I’ve rode horses before and have never had this issue," Remi Bader, who has more than 2 million followers on TikTok, wrote in the caption of her video. Remi Bader says a ranch wouldn't allow ...
For older adults with diabetes, having a more stable hemoglobin A1c (HbA1c) level over time may be associated with a lower risk of Alzheimer disease and dementia, a new study finds.
Alzheimer's disease (AD) is a neurodegenerative disease and the most common cause of dementia; it usually occurs in old age. Familial Alzheimer's disease (FAD or EOFAD for early onset) is an inherited and uncommon form of AD. Familial AD usually strikes earlier in life, defined as before the age of 65.
Rhabdomyolysis (shortened as rhabdo) is a condition in which damaged skeletal muscle breaks down rapidly, often due to high intensity exercise over a short period. [6] [4] [5] Symptoms may include muscle pains, weakness, vomiting, and confusion. [3] [4] There may be tea-colored urine or an irregular heartbeat.