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Structure of a gene regulatory network Control process of a gene regulatory network. A gene (or genetic) regulatory network (GRN) is a collection of molecular regulators that interact with each other and with other substances in the cell to govern the gene expression levels of mRNA and proteins which, in turn, determine the function of the cell.
Granulin is a protein that in humans is encoded by the GRN gene. [5] [6] [7] Each granulin protein is cleaved from the precursor progranulin, a 593 amino-acid-long and 68.5 kDa protein. [8]
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The concept of gene co-expression networks was first introduced by Butte and Kohane in 1999 as relevance networks. [6] They gathered the measurement data of medical laboratory tests (e.g. hemoglobin level ) for a number of patients and they calculated the Pearson correlation between the results for each pair of tests and the pairs of tests which showed a correlation higher than a certain level ...
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Printable version; In other projects ... GRN may refer to: Broadcasting. Global Radio News, a journalism organization; Government Radio Network (Australia) ...
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