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The nuclear receptor 4A1 (NR4A1 for "nuclear receptor subfamily 4 group A member 1") also known as Nur77, TR3, and NGFI-B is a protein that in humans is encoded by the NR4A1 gene. [ 5 ] [ 6 ] Nuclear receptor 4A1 (NR4A1) is a member of the NR4A nuclear receptor family [ 7 ] of intracellular transcription factors .
The classic "canonical" NF-κB complex is a heterodimer of p50 and RelA, [1] as shown. NF-κB waits for activation in the cytosol, complexed with the inhibitory protein IκBα . Various extracellular signals can enter the cell via membrane receptors and activate the enzyme IκB kinase (IKK).
Transcobalamin I (TC-1), also known as haptocorrin (HC), R-factor, and R-protein is encoded in the human by the TCN1 gene. TC-1 is a glycoprotein produced by the salivary glands of the mouth. It primarily serves to protect cobalamin (Vitamin B12) from acid degradation in the stomach by producing a HC-Vitamin B 12 complex.
Kinesin is a protein functioning as a molecular biological machine. It uses protein domain dynamics on nanoscales. A protein complex or multiprotein complex is a group of two or more associated polypeptide chains. Protein complexes are distinct from multidomain enzymes, in which multiple catalytic domains are found in a single polypeptide chain ...
The complex has no reaction with hydrogen gas, and cannot carry oxygen as salcomine does. It would, however, react with hydrogen in the presence of sodium hydroxide , a catalytic amount of platinum metal, or a reduced cobaloxime, therefore once the reduction occurs, the hydrogenation would occur much more rapidly as there is autocatalysis .
Few periods of life are more closely monitored and supervised than during one's pregnancy. Throughout this time, trained medical professionals conduct a series of prenatal visits with the mother ...
The cytochrome b 6 f complex is a dimer, with each monomer composed of eight subunits. [3] These consist of four large subunits: a 32 kDa cytochrome f with a c-type cytochrome, a 25 kDa cytochrome b 6 with a low- and high-potential heme group, a 19 kDa Rieske iron-sulfur protein containing a [2Fe-2S] cluster, and a 17 kDa subunit IV; along with four small subunits (3-4 kDa): PetG, PetL, PetM ...
From January 2008 to May 2009, if you bought shares in companies when Richard C. Perry joined the board, and sold them when he left, you would have a -38.5 percent return on your investment, compared to a -38.2 percent return from the S&P 500.