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Benzocaine, sold under the brand name Orajel amongst others, is a local anesthetic, belonging to the amino ester drug class, commonly used as a topical painkiller or in cough drops.
Buccal administration may provide better bioavailability of some drugs and a more rapid onset of action compared to oral administration because the medication does not pass through the digestive system and thereby avoids first pass metabolism. [1] Drug forms for buccal administration include tablets and thin films.
Cepacol (/ ˈ s iː p ə k ɒ l / SEE-pə-kol styled Cēpacol) is an American brand of personal hygiene products, as well as for relief of sore throat. It is distributed in the US by Reckitt. [1] The brand was originally owned by J.B. Williams. Following acquisition by Combe Incorporated, Combe Incorporated sold Cepacol to Reckitt Benckiser in ...
Benzonatate was first made available in the United States in 1958 as a prescription medication for the treatment of cough in individuals over the age of 10. [ 24 ] [ 25 ] There is a variety of prescription opioid -based cough relievers, such as hydrocodone and codeine , but have unwanted side effects and potential of abuse and diversion. [ 22 ]
Rectal administration (colloquially known as boofing or plugging) uses the rectum as a route of administration for medication and other fluids, which are absorbed by the rectum's blood vessels, [Note 1] and flow into the body's circulatory system, which distributes the drug to the body's organs and bodily systems.
The product Sucrets was introduced in Baltimore, Maryland, by Sharp & Dohme in 1932. [3]In 1966 the Federal Trade Commission ordered Merck and Company to discontinue the false claims of germ-killing and pain-relieving properties for its Sucrets and Children's Sucrets throat lozenges. [4]
The opposite of an indication is a contraindication, [4] a reason to withhold a certain medical treatment because the risks of treatment clearly outweigh the benefits. In the United States, indications for prescription drugs are approved by the FDA. Indications are included in the Indications and Usage section of the Prescribing Information.
Modafinil is a central nervous system (CNS) stimulant medication used to treat sleepiness due to narcolepsy, shift work sleep disorder, and obstructive sleep apnea. It is often used off-label as a nootropic. Prazosin (Minipress) for nightmares: prazosin is approved for the use of hypertension. A 2012 systematic review showed a small benefit for ...