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CD1 (cluster of differentiation 1) is a family of glycoproteins expressed on the surface of various human antigen-presenting cells.CD1 glycoproteins are structurally related to the class I MHC molecules, however, in contrast to MHC class 1 proteins, they present lipids, glycolipids and small molecules antigens, from both endogenous and pathogenic proteins, to T cells and activate an immune ...
Neuropilin-1 (NP-1), NRP1 or BDCA-4, has a wide range of functions. On neurons , it is a receptor for axon growth guidance class-3 semaphorins SEMA3A and plexin-1, on endothelial and some tumor cells it is a VEGF 165 receptor, and on plasmacytoid dendritic cells it has a similar role to CD303 but does not decrease interferon production upon ...
The CD nomenclature was proposed and established in the 1st International Workshop and Conference on Human Leukocyte Differentiation Antigens (HLDA), held in Paris in 1982. [4] [5] This system was intended for the classification of the many monoclonal antibodies (mAbs) generated by different laboratories around the world against epitopes on the surface molecules of leukocytes (white blood cells).
952 12494 Ensembl ENSG00000004468 ENSMUSG00000029084 UniProt P28907 P56528 RefSeq (mRNA) NM_001775 NM_007646 RefSeq (protein) NP_001766 NP_031672 Location (UCSC) Chr 4: 15.78 – 15.85 Mb Chr 5: 44.03 – 44.07 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase, is a glycoprotein found on the surface of many ...
CD14 is expressed mainly by macrophages and (at 10-times lesser extent) by neutrophils.It is also expressed by dendritic cells.The soluble form of the receptor (sCD14) is secreted by the liver and monocytes and is sufficient in low concentrations to confer LPS-responsiveness to cells not expressing CD14. mCD14 and sCD14 are also present on enterocytes.
Neural cell adhesion molecule (NCAM), also called CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle.Although CD56 is often considered a marker of neural lineage commitment due to its discovery site, CD56 expression is also found in, among others, the hematopoietic system.
CD1D is the human gene that encodes the protein CD1d, [5] a member of the CD1 (cluster of differentiation 1) family of glycoproteins expressed on the surface of various human antigen-presenting cells. They are non-classical MHC proteins, related to the class I MHC proteins, and are involved in the presentation of lipid antigens to T cells. CD1d ...
15894 Ensembl ENSG00000090339 ENSMUSG00000037405 UniProt P05362 P13597 RefSeq (mRNA) NM_000201 NM_010493 RefSeq (protein) NP_000192 NP_034623 Location (UCSC) Chr 19: 10.27 – 10.29 Mb Chr 9: 20.93 – 20.94 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse ICAM-1 (Intercellular Adhesion Molecule 1) also known as CD54 (C luster of D ifferentiation 54) is a protein that in humans is ...