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Metoprolol is a beta blocker, or an antagonist of the β-adrenergic receptors. It is specifically a selective antagonist of the β 1-adrenergic receptor and has no intrinsic sympathomimetic activity. [37] Metoprolol exerts its effects by blocking the action of certain neurotransmitters, specifically adrenaline and noradrenaline.
The β-blockers are an immensely important class of drugs due to their high prevalence of use. The discovery of β-blockers reaches back to more than 100 years ago, when early investigators came up with the idea that catecholamines were binding selectively to receptor-like structures and that this was the cause of their pharmacological actions. [3]
A disfluence or nonfluence is a non-pathological hesitance when speaking, the use of fillers (“like” or “uh”), or the repetition of a word or phrase. This needs to be distinguished from a fluency disorder like stuttering with an interruption of fluency of speech, accompanied by "excessive tension, speaking avoidance, struggle behaviors, and secondary mannerism".
A speech-to-text reporter (STTR), also known as a captioner, is a person who listens to what is being said and inputs it, word for word (), as properly written texts.Many captioners use tools (such as a shorthand keyboard, speech recognition software, or a computer-aided transcription software system), which commonly convert verbally communicated information into written words to be composed ...
While negative inotropism may precipitate or exacerbate heart failure in the short term, certain beta blockers (e.g. carvedilol, bisoprolol and metoprolol) have been believed to reduce long-term morbidity and mortality in congestive heart failure. [13] Examples of negative inotropic agents include: Beta blockers [14]
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Nick Dunlap, a 20-year-old sophomore who plays golf for the University of Alabama, won the American Express tournament Sunday at the PGA West golf course in La Quinta, California.
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