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  2. Immune thrombocytopenic purpura - Wikipedia

    en.wikipedia.org/wiki/Immune_thrombocytopenic...

    In a phase 1-2 open-label study treatment with CM313, a novel anti-CD38 monoclonal antibody, rapidly boosted platelet levels in adults with ITP by inhibiting antibody-dependent cell-mediated cytotoxicity on platelets; maintained long-term efficacy by clearing plasma cells; and was associated with low-grade toxic effects.

  3. Thrombotic thrombocytopenic purpura - Wikipedia

    en.wikipedia.org/wiki/Thrombotic...

    Thrombotic thrombocytopenic purpura (TTP) initially presents with a range of symptoms that may include severe thrombocytopenia (platelet count usually < 30,000/mm³), microangiopathic hemolytic anemia (evidenced by schistocytes in the blood smear), and various clinical signs such as petechiae, purpura, neurologic symptoms, myocardial ischemia ...

  4. Neonatal alloimmune thrombocytopenia - Wikipedia

    en.wikipedia.org/wiki/Neonatal_alloimmune...

    Therefore, ITP is a significant cause of fetal and neonatal immune thrombocytopenia. Approximately 10% of newborns affected by ITP will have platelet counts <50,000 μL −1 and 1% to 2% will have a risk of intracerebral hemorrhage comparable to infants with NAIT. [1] [8]

  5. UpToDate - Wikipedia

    en.wikipedia.org/wiki/UpToDate

    The UpToDate system is an evidence-based clinical resource. It includes a collection of medical and patient information, access to Lexicomp drug monographs and drug-to-drug interactions, and a number of medical calculators. UpToDate is written by over 7,100 physician authors, editors, and peer reviewers. It is available both via the Internet ...

  6. Thrombocytopenic purpura - Wikipedia

    en.wikipedia.org/wiki/Thrombocytopenic_purpura

    Download QR code; Print/export ... Diagnosis is done by the help of symptoms and only blood count abnormality is thrombocytopenia. [citation needed] Treatment

  7. Heparin-induced thrombocytopenia - Wikipedia

    en.wikipedia.org/wiki/Heparin-induced...

    The timing, severity of the thrombocytopenia, the occurrence of new thrombosis, and the presence of alternative explanations, all determine the likelihood that HIT is present. A commonly used score to predict the likelihood of HIT is the "4 Ts" score introduced in 2003. [10] A score of 0–8 points is generated; if the score is 0–3, HIT is ...

  8. Pseudothrombocytopenia - Wikipedia

    en.wikipedia.org/wiki/Pseudothrombocytopenia

    Pseudothrombocytopenia (PTCP) or spurious thrombocytopenia is an in-vitro sampling problem which may mislead the diagnosis towards the more critical condition of thrombocytopenia. The phenomenon may occur when the anticoagulant used while testing the blood sample causes clumping of platelets which mimics a low platelet count. [ 1 ]

  9. Giant platelet disorder - Wikipedia

    en.wikipedia.org/wiki/Giant_platelet_disorder

    There has been no general recommendation for treatment of patients with giant platelet disorders, as there are many different specific classifications to further categorize this disorder which each need differing treatments. Platelet transfusion is the main treatment for people presenting with bleeding symptoms.

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