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  2. History of coronavirus - Wikipedia

    en.wikipedia.org/wiki/History_of_coronavirus

    The history of coronaviruses is an account of the discovery of the diseases caused by coronaviruses and the diseases they cause. It starts with the first report of a new type of upper-respiratory tract disease among chickens in North Dakota, U.S., in 1931.

  3. CRISPR - Wikipedia

    en.wikipedia.org/wiki/CRISPR

    The spacer regions of CRISPR-Cas systems are taken directly from foreign mobile genetic elements and thus their long-term evolution is hard to trace. [157] The non-random evolution of these spacer regions has been found to be highly dependent on the environment and the particular foreign mobile genetic elements it contains. [158]

  4. Timeline of the COVID-19 pandemic - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_the_COVID-19...

    The timeline of the COVID-19 pandemic lists the articles containing the chronology and epidemiology of SARS-CoV-2, [1] the virus that causes the coronavirus disease 2019 and is responsible for the COVID-19 pandemic. The first human cases of COVID-19 occurred in Wuhan, People's Republic of China, on or about 17 November 2019. [2]

  5. Timeline of biotechnology - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_biotechnology

    The world's first COVID-19 drug designed by generative AI is approved for human use, with clinical trials expected to begin in China. The new drug, ISM3312, is developed by Insilico Medicine. [389] A new AI algorithm developed by Baidu is shown to boost the antibody response of COVID-19 mRNA vaccines by 128 times. [390]

  6. Cas12a - Wikipedia

    en.wikipedia.org/wiki/Cas12a

    The CRISPR-Cas12a system consist of a Cas12a enzyme and a guide RNA that finds and positions the complex at the correct spot on the double helix to cleave target DNA. CRISPR-Cas12a systems activity has three stages: [3] Adaptation: Cas1 and Cas2 proteins facilitate the adaptation of small fragments of DNA into the CRISPR array.

  7. Social history of viruses - Wikipedia

    en.wikipedia.org/wiki/Social_history_of_viruses

    A related coronavirus emerged in Wuhan, China in November 2019 and spread rapidly around the world. [269] Subsequently named severe acute respiratory syndrome coronavirus 2 , infections with the virus caused a pandemic with a case fatality rate of around 2% in healthy people under the age of 50, to around 15% in those aged over 80 particularly ...

  8. SARS-CoV-2 - Wikipedia

    en.wikipedia.org/wiki/SARS-CoV-2

    SARS-CoV-2 is the seventh known coronavirus to infect people, after 229E, NL63, OC43, HKU1, MERS-CoV, and the original SARS-CoV. [105] Like the SARS-related coronavirus implicated in the 2003 SARS outbreak, SARS‑CoV‑2 is a member of the subgenus Sarbecovirus (beta-CoV lineage B). [106] [107] Coronaviruses undergo frequent recombination. [108]

  9. Origin of SARS-CoV-2 - Wikipedia

    en.wikipedia.org/wiki/Origin_of_SARS-CoV-2

    The FBI concluded with "moderate confidence" that COVID-19 may have been created in a laboratory, based in part on genomic analysis conducted by scientists at the National Center for Medical Intelligence. [98] On 20 March 2023, the COVID-19 Origin Act of 2023 was signed into law. On June 23, 2023, the Biden administration released its report ...