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Laser ablation or photoablation (also called laser blasting [1] [2] [3]) is the process of removing material from a solid (or occasionally liquid) surface by irradiating it with a laser beam. At low laser flux, the material is heated by the absorbed laser energy and evaporates or sublimates .
Pulsed Nd:YAG and Er:YAG lasers are used in laser tattoo removal and laser range finders among other applications. Pulsed lasers are also used in soft-tissue surgery. When a laser beam comes into contact with soft-tissue, one important factor is to not overheat surrounding tissue, so necrosis can be prevented. [3]
Low-intensity extracorporeal shock wave therapy has been used as a treatment for erectile dysfunction. [23] It differs from palliative options by aiming to restore natural erectile function by inducing cellular microtrauma, triggering the release of angiogenic factors and promoting neovascularization in treated tissue. This mechanism is ...
Pulsed field ablation (PFA) is a non-thermal (not using extreme heat or cold) method of biological ablation (removal of structure or functionality) utilizing high-amplitude pulsed (microsecond duration) electric fields to create irreversible electroporation in tissues. [1] [2] It is used most widely to treat tumors or cardiac arrhythmias. [3]
Common current ultrashort pulse laser technologies include Ti-sapphire lasers and dye lasers. High output peak power usually requires chirped pulse amplification of a seed pulse from a modelocked laser. Dealing with high optical powers also needs the nonlinear optical phenomena to be taken in account. [citation needed]
Incomplete ablation within targeted tumors - The originally threshold for IRE of cells was approximately 600 V/cm with 8 pulses, a pulse duration of 100 μs, and a frequency of 10 Hz. [34] Qin et al. later discovered that even at 1,300 V/cm with 99 pulses, a pulse duration of 100 μs, and 10 Hz, there were still islands of viable tumor cells ...
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