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1942 – benzylpenicillin, the first penicillin; 1942 – gramicidin S, the first peptide antibiotic; 1942 – sulfadimidine; 1943 – sulfamerazine; 1944 – streptomycin, the first aminoglycoside [2] 1947 – sulfadiazine; 1948 – chlortetracycline, the first tetracycline; 1949 – chloramphenicol, the first amphenicol [2] 1949 – neomycin
In 1907 Alfred Bertheim synthesized Arsphenamine, the first man-made antibiotic. In 1927 Erik Rotheim patented the first aerosol spray can. In 1933 Robert Pauli Scherer created a method to develop softgels. William Roberts studies about penicillin were continued by Alexander Fleming, who in 1928 concluded that penicillin had an antibiotic ...
The history of penicillin follows observations and discoveries of evidence of antibiotic activity of the mould Penicillium that led to the development of penicillins that became the first widely used antibiotics. Following the production of a relatively pure compound in 1942, penicillin was the first naturally-derived antibiotic.
Arsphenamine, also known as Salvarsan or compound 606, is an antibiotic drug that was introduced at the beginning of the 1910s as the first effective treatment for the deadly infectious diseases syphilis, relapsing fever, and African trypanosomiasis. [2] [3] This organoarsenic compound was the first modern antimicrobial agent. [4]
Azathioprine is an Immunosuppressive drug used in rheumatoid arthritis, granulomatosis with polyangiitis, Crohn's disease, ulcerative colitis, and in kidney transplants to prevent rejection first synthesized by George H. Hitchings and Gertrude B. Elion in 1957 . [3] [4] [5] AZT Flossie Wong-Staal was the first scientist to clone HIV and map its ...
6000 BCE – Yogurt and cheese made with lactic acid-producing bacteria by various people. 4500 BCE – Egyptians bake leavened bread using yeast. [1] 500 BCE – Moldy soybean curds used as an antibiotic. 300 BCE – The Greeks practice crop rotation for maximum soil fertility. [2] 100 AD – Chinese use chrysanthemum as a natural insecticide ...
In 1858, Mason created jars that were made of transparent glass with a screw-on top. Inside the flat metal lids, he placed a rubber ring, which was crucial to making the container airtight.
Production of antibiotics is a naturally occurring event, that thanks to advances in science can now be replicated and improved upon in laboratory settings. Due to the discovery of penicillin by Alexander Fleming, and the efforts of Florey and Chain in 1938, large-scale, pharmaceutical production of antibiotics has been made possible.