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Diphtheria is an infection caused by the bacterium Corynebacterium diphtheriae. [2] Most infections are asymptomatic or have a mild clinical course, but in some outbreaks, the mortality rate approaches 10%. [1]
Diphtheria antitoxin (DAT) is a medication made up of antibodies used in the treatment of diphtheria. [1] [2] It is no longer recommended for prevention of diphtheria. [2] [3] It is administered through injection into a vein or muscle. [2] Side effects are common. [3] They include serum sickness and allergic reactions including anaphylaxis. [2]
Diphtheria vaccine is a toxoid vaccine against diphtheria, an illness caused by Corynebacterium diphtheriae. [2] Its use has resulted in a more than 90% decrease in number of cases globally between 1980 and 2000. [ 3 ]
Corynebacterium diphtheriae [a] is a Gram-positive pathogenic bacterium that causes diphtheria. [2] It is also known as the Klebs–Löffler bacillus because it was discovered in 1884 by German bacteriologists Edwin Klebs (1834–1912) and Friedrich Löffler (1852–1915). [3]
tetanus, diphtheria, and acellular pertussis (Tdap) Part D also covers travel vaccines that the CDC’s Advisory Committee on Immunization Practices (ACIP) recommends, such as vaccines for: yellow ...
Diphtheria and tetanus toxoids and whole-cell [10] pertussis (DTP; now also "DTwP" to differentiate from the broader class of triple-combination vaccines) [9] vaccination was licensed in 1949. [13] Since the introduction of the combination vaccine, there has been an extensive decline in the incidence of pertussis, or whooping cough, the disease ...
Antitoxins to diphtheria and tetanus toxins were produced by Emil Adolf von Behring and his colleagues from 1890 onwards. The use of diphtheria antitoxin for the treatment of diphtheria was regarded by The Lancet as the "most important advance of the [19th] Century in the medical treatment of acute infectious disease".
Benzathine benzylpenicillin, also known as benzathine penicillin G (BPG), is an antibiotic medication useful for the treatment of a number of bacterial infections. [3] Specifically it is used to treat strep throat, diphtheria, syphilis, and yaws. [3] [5] It is also used to prevent rheumatic fever. [5] It is given by injection into a muscle.