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Alcohol-related brain damage [1] [2] alters both the structure and function of the brain as a result of the direct neurotoxic effects of alcohol intoxication or acute alcohol withdrawal. Increased alcohol intake is associated with damage to brain regions including the frontal lobe , [ 3 ] limbic system , and cerebellum , [ 4 ] with widespread ...
The long-term impact of alcohol on the brain has become a growing area of research focus. While researchers have found that moderate alcohol consumption in older adults is associated with better cognition and well-being than abstinence, [1] excessive alcohol consumption is associated with widespread and significant brain lesions.
Alcohol acts as a general central nervous system depressant, but it also affects some specific areas of the brain to a greater extent than others. Memory impairment caused by alcohol has been linked to the disruption of hippocampal function—particularly affecting gamma-Aminobutyric acid (GABA) and N-methyl-D-aspartate (NMDA) neurotransmission which negatively impacts long-term potentiation ...
Alcohol is a tiny molecule, bathing nearly every cell in the body when we drink. The basic trajectory of liquor in the body is from a person's mouth, through the esophagus, to the stomach ...
Failure to manage the alcohol withdrawal syndrome appropriately can lead to permanent brain damage or death. [11] Acamprosate, a drug used to promote abstinence from alcohol, an NMDA antagonist drug, reduces excessive glutamate activity in the central nervous system and thereby may reduce excitotoxicity and withdrawal related brain damage. [12 ...
Serotonin syndrome is a potentially life-threatening drug reaction that causes the body to have too much serotonin. It can be caused by certain drug interactions, as well as drinking alcohol while ...
Alcohol can cause brain damage, Wernicke's encephalopathy and Alcoholic Korsakoff syndrome which frequently occur simultaneously, known as Wernicke–Korsakoff syndrome. [72] Lesions , or brain abnormalities, are typically located in the diencephalon which result in anterograde and retrograde amnesia , or memory loss.
“Take alcohol seriously as a drug with risks. Look honestly at how it is affecting your life and ask for help if you need it to cut down or quit,” he said. Harb recommended prioritizing other ...