Search results
Results from the WOW.Com Content Network
Continuing the maintenance dose for about 4 to 5 half-lives (t 1/2) of the drug will approximate the steady state level. [1] One or more doses higher than the maintenance dose can be given together at the beginning of therapy with a loading dose. [2] A loading dose is most useful for drugs that are eliminated from the body relatively slowly ...
"Practice parameter for the assessment and treatment of children and adolescents with bipolar disorder". Journal of the American Academy of Child and Adolescent Psychiatry. 46 (1): 107– 25. doi: 10.1097/01.chi.0000242240.69678.c4. PMID 17195735. "Mood Disorder Questionnaire for Parents of Adolescents" (PDF). Bipolar Network News. 28 August 2012.
A variety of other agents have been tried in bipolar disorder, including benzodiazepines, calcium channel blockers, L-methylfolate, and thyroid hormone. [2] Modafinil (Provigil) and pramipexole (Mirapex) have been suggested for treating cognitive dysfunction associated with bipolar depression, but evidence supporting their use is quite limited.
The KSADS-P was the first version of the K-SADS, developed by Chambers and Puig-Antich in 1978 as a version of the Schedule for Affective Disorders and Schizophrenia adapted for use with children and adolescents 6–19 years old. This version rephrased the SADS to make the wording of the questionnaire pertain to a younger age group. [1]
The WHO Model List of Essential Medicines for Children (aka Essential Medicines List for Children [1] or EMLc [1]), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe in children up to twelve years of age to meet the most important needs in a health system. [2] [3]
It is administered to parents for them to rate their children between ages 5–17. The 10 items include symptoms such as elated mood, high energy, irritability and rapid changes in mood and energy as indicators of potential juvenile bipolar disorder. [5] The PhenX Toolkit uses this instrument as its child protocol for Hypomania/Mania Symptoms. [6]
Diagnosis is made based on a clinical interview by a licensed mental health professional. There are no blood tests or imaging to diagnose bipolar disorder. [10] Pediatric bipolar disorder can be difficult to diagnose, especially in children under 11–12 years as they may be unable to properly self-assess and communicate any possible symptoms. [11]
FDA approved for bipolar disorder maintenance therapy, not for acute mood problems like depression or mania/hypomania. [10] The usual target dose is 100–200 mg daily, titrated to by 25 mg increments every 2 weeks. [11] Lamotrigine can cause Stevens–Johnson syndrome, a very rare but potentially fatal skin condition. [10] Carbamazepine