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A goitre, or goiter, is a swelling in the neck resulting from an enlarged thyroid gland. [1] [2] A goitre can be associated with a thyroid that is not functioning properly. Worldwide, over 90% of goitre cases are caused by iodine deficiency. [3] The term is from the Latin gutturia, meaning throat.
Iodine deficiency is the most common cause of primary hypothyroidism and endemic goiter worldwide. [8] [9] In areas of the world with sufficient dietary iodine, hypothyroidism is most commonly caused by the autoimmune disease Hashimoto's thyroiditis (chronic autoimmune thyroiditis). [8] [9] Hashimoto's may be associated with a goiter.
Rarely goiters can cause compression of the airway, compression of the vessels in the neck, or difficulty swallowing. [7] Tumors, often called thyroid nodules, can also have many different symptoms ranging from hyperthyroidism to hypothyroidism to swelling in the neck and compression of the structures in the neck. [7]
The leading cause of hypothyroidism is Hashimoto’s disease (also known as Hashimoto’s thyroiditis, chronic autoimmune thyroiditis or lymphocytic thyroiditis), per Cleveland Clinic.
2 Cause. 3 Diagnosis. ... Dyshormogenetic goiter: ... Patients develop hypothyroidism with a goiter. [citation needed] Cause
Between 1993 and 2001, per 1000 women, the disease was found varying between 3.9 and 4.89. Between 1994 and 2001, per 1000 men, the disease increased from 0.65 to 1.01. [124] Changes in the definition of hypothyroidism and treatment options modify the incidence and prevalence of the disease overall.
Iodine deficiency is a lack of the trace element iodine, an essential nutrient in the diet.It may result in metabolic problems such as goiter, sometimes as an endemic goiter as well as congenital iodine deficiency syndrome due to untreated congenital hypothyroidism, which results in developmental delays and other health problems.
De Quervain's thyroiditis, also known as subacute granulomatous thyroiditis or giant cell thyroiditis, is a self-limiting inflammatory illness of the thyroid gland. [1] De Quervain thyroiditis is characterized by fever, flu-like symptoms, a painful goiter, and neck pain.
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