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RNP procedures were introduced in the PANS-OPS (ICAO Doc 8168), which became applicable in 1998. These RNP procedures were the predecessor of the current PBN concept, whereby the performance for operation on the route is defined (in lieu of flight elements such as flyover procedures, variability in flight paths, and added airspace buffer), but they resulted in no significant design advantages.
A ribonucleoprotein particle (RNP) is a complex formed between RNA and RNA-binding proteins (RBPs). [1] The term RNP foci can also be used to denote intracellular compartments involved in processing of RNA transcripts .
ICAO performance-based navigation (PBN) specifies that aircraft required navigation performance (RNP) and area navigation (RNAV) systems performance requirements be defined in terms of accuracy, integrity, availability, continuity, and functionality required for the proposed operations in the context of a particular airspace, when supported by the appropriate navigation infrastructure.
Ribonucleoprotein Networks Analyzed by Mutational Profiling (RNP-MaP) is a strategy for probing RNA-protein networks and protein binding sites at a nucleotide resolution. Information about RNP assembly and function can facilitate a better understanding of biological mechanisms.
The RNA component of human telomerase (hTERC) contains an H/ACA domain for pre-RNP formation and nucleolar localization of the telomerase RNP itself. [13] The H/ACA snoRNP has been implicated in the rare genetic disease dyskeratosis congenita (DKC) due to its affiliation with human telomerase. Mutations in the protein component of the H/ACA ...
RNA recognition motif, RNP-1 is a putative RNA-binding domain of about 90 amino acids that are known to bind single-stranded RNAs. It was found in many eukaryotic proteins. [ 1 ] [ 2 ] [ 3 ]
In C. elegans, RNA-binding proteins including FOG-1, MOG-1/-4/-5 and RNP-4 regulate germline and somatic sex determination. Furthermore, several RBPs such as GLD-1, GLD-3, DAZ-1, PGL-1 and OMA-1/-2 exert their regulatory functions during meiotic prophase progression, gametogenesis , and oocyte maturation .
As described in a 2022 review, [7] long-term memory utilizes messenger RNP. Rats with a new, strong long-term memory due to contextual fear conditioning have reduced expression of about 1,000 genes and increased expression of about 500 genes in the hippocampus 24 hours after training, thus exhibiting modified expression of 9.17% of the rat hippocampal genome.