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The focus of translational neuroscience research is to investigate the molecular mechanisms for these disorders, and to investigate the mechanisms of drug delivery to treat these disorders, including an investigation into the impact of the blood-brain barrier on drug delivery, and the role of the body's immune system in neurodegenerative disorders.
Stephen Louis Macknik (/ ˈ m æ k n ɪ k / MAK-nik; [1] born August 9, 1968) is an American neuroscientist and science writer. He is a Professor of Ophthalmology, Neurology, and Physiology & Pharmacology [2] at the State University of New York, Downstate Medical Center, where he directs the Laboratory of Translational Neuroscience.
Elizabeth Gould (born 1962) [1] is an American neuroscientist and the Dorman T. Warren Professor of Psychology at Princeton University. [2] [3] She was an early investigator of adult neurogenesis in the hippocampus, a research area that continues to be controversial.
Dame Pamela Jean Shaw DBE FMedSci is a British consultant neurologist and professor of neurology at the University of Sheffield.She is the founder and director of the Sheffield Institute for Translational Neuroscience (), and in 2019 was appointed to lead the National Institute for Health Research (NIHR) Sheffield Biomedical Research Centre.
Leanne M Williams. Leanne M. Williams is a professor in psychiatry and behavioural sciences at Stanford University. [1] She is also the founding director of the Stanford Center for Precision Mental Health and Wellness and of the Precision Psychiatry and Translational Neuroscience Laboratory in the Stanford Medical School.
Nedergaard's discovery of the glymphatic system was honored as one of Science Magazine's ten "Breakthroughs of the Year" in 2013. [9] In 2014, she accepted a Novo Nordisk Foundation Laureate Research Grant in 2014 to assist in establishing a Center for Basic and Translational Neuroscience at the University of Copenhagen. [10]
The Journal of Neural Transmission is a monthly peer-reviewed medical journal covering clinical neurology and translational neuroscience. It was established in 1950 by Carmen Coronini and Alexander Sturm as Acta Neurovegetativa. [1] It was renamed to the Journal of Neuro-Visceral Relations in 1968 and to its current title in 1972.
Post-translational feedback loops (PTFLs) involved in clock gene regulation have also been uncovered, often working in tandem with the TTFL model. In both mammals and plants, post-translational modifications such as phosphorylation and acetylation regulate the abundance and/or activity of clock genes and proteins.