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Late-life depression refers to depression occurring in older adults and has diverse presentations, including as a recurrence of early-onset depression, a new diagnosis of late-onset depression, and a mood disorder resulting from a separate medical condition, substance use, or medication regimen. [1]
Subcortical ischemic depression, also known as vascular depression, is a medical condition most commonly seen in older people with major depressive disorder. Subcortical ischemic depression refers to vascular depression specifically due to lesions and restricted blood flow, known as ischemia , in certain parts of the brain.
In their lifetime, 20% to 25% of women and 7% to 12% of men will have a major depressive episode. [35] The peak period of development is between the ages of 25 and 44. [3] The onset of major depressive episodes or MDD often occurs in people in their mid-20s and less often in those over 65.
They note that about 30% of people with depression do not adequately respond to treatment. They say the subtypes may help identify potential treatment responses for things such as antidepressants ...
The risk factors [110] for treatment resistant depression are: the duration of the episode of depression, severity of the episode, if bipolar, lack of improvement in symptoms within the first couple of treatment weeks, anxious or avoidant and borderline comorbidity and old age. Treatment resistant depression is best handled with a combination ...
An ocular manifestation of a systemic disease is an eye condition that directly or indirectly results from a disease process in another part of the body. There are many diseases known to cause ocular or visual changes.
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