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Alternative online IC50 calculator (www.ic50.org) based on Python, NumPy, SciPy and Matplotlib; ELISA IC50/EC50 Online Tool (link seems broken) IC50 to pIC50 calculator; Online tool for analysis of in vitro resistance to antimalarial drugs; IC50-to-Ki converter of an inhibitor and enzyme that obey classic Michaelis-Menten kinetics
Template documentation The half maximal inhibitory concentration ( IC50 ) is often referred to as "IC 50 ". This template is provided to give a link to the former while displaying the latter.
Biological responses to ligand concentrations typically follow a sigmoidal function. The inflection point at which the increase in response with increasing ligand concentration begins to slow is the EC 50, which can be mathematically determined by derivation of the best-fit line.
The parameters of the dose response curve reflect measures of potency (such as EC50, IC50, ED50, etc.) and measures of efficacy (such as tissue, cell or population response). A commonly used dose–response curve is the EC 50 curve, the half maximal effective concentration, where the EC 50 point is defined as the inflection point of the curve.
Excel's storage of numbers in binary format also affects its accuracy. [3] To illustrate, the lower figure tabulates the simple addition 1 + x − 1 for several values of x. All the values of x begin at the 15 th decimal, so Excel must take them into account. Before calculating the sum 1 + x, Excel first approximates x as a binary number
Toxic units (TU) are used in the field of toxicology to quantify the interactions of toxicants in binary mixtures of chemicals. [1] A toxic unit for a given compound is based on the concentration at which there is a 50% effect (ex. EC50) for a certain biological endpoint.
Virus quantification is counting or calculating the number of virus particles (virions) in a sample to determine the virus concentration. It is used in both research and development (R&D) in academic and commercial laboratories as well as in production situations where the quantity of virus at various steps is an important variable that must be monitored.
Several templates and tools are available to assist in formatting, such as reFill (documentation) and Citation bot (documentation). ( August 2022 ) ( Learn how and when to remove this message ) Programmable calculators are calculators that can automatically carry out a sequence of operations under control of a stored program .