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Levothyroxine is a synthetic form of thyroxine (T 4), which is secreted by the thyroid gland. Levothyroxine and thyroxine are chemically identical: natural thyroxine is also in the "levo" chiral form, the difference is only in terminological preference. T 4 is biosynthesized from tyrosine. Approximately 5% of the US population suffers from over ...
Thyroxine, also known as T 4, is a hormone produced by the thyroid gland.It is the primary form of thyroid hormone found in the blood and acts as a prohormone of the more active thyroid hormone, triiodothyronine (T 3). [1]
Wockhardt is an Indian pharmaceutical and biotechnology company headquartered in Mumbai, India. It produces formulations , biopharmaceuticals , nutrition products, vaccines and active pharmaceutical ingredients (APIs). [ 4 ]
They inhibit release of thyroid hormones by the thyroid gland.The most studied drug in this class is lithium, which inhibits thyroid hormone secretion by inhibiting iodotyrosine coupling, thyroidal iodide uptake, and alteration in structure of thyroglobulin, [10] a protein which acts as a substrate for the synthesis of thyroid hormones and storage of inactive forms of T3, T4 and iodine within ...
They recommend levothyroxine as the preferred treatment. Some practitioners refuse to use desiccated thyroid. [9] Each 64.8 mg (one grain) of thyroid extract contains approximately 38 μg and 9 μg of measurable levothyroxine (T4) and liothyronine (T3), respectively. [1] Arguments against desiccated thyroid include:
Liothyronine may be used when there is an impaired conversion of T 4 to T 3 in peripheral tissues. [2] The dose of liothyronine for hypothyroidism is a lower amount than levothyroxine due it being a higher concentrated synthetic medication. [2]
Wockhardt Hospitals Ltd is an Indian for-profit private hospital network headquartered in Mumbai. [4] The chain of hospitals is owned by the promoters of Wockhardt , [ 5 ] a multinational pharmaceutical company. [ 6 ]
Habil Khorakiwala is the founder and Chairman of Indian multinational pharmaceutical and biotechnology company Wockhardt. [1] He founded Wockhardt in 1967, [2] which since then has grown into one of the top Indian makers of generic drugs, formulations, biopharmaceuticals, nutrition products, vaccines, active pharmaceutical ingredients (APIs) and a chain of advanced Super Speciality Hospitals.