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Taking minoxidil with the following medications may lower blood pressure and cause changes in your heart rate: Diphenhydramine (Benadryl) Bupropion (Wellbutrin)
Like topical minoxidil, oral minoxidil can cause side effects. These include: Hypertrichosis (excessive body hair growth) Tachycardia (fast heart rate) Transient dizziness. Fluid retention. Hair ...
Oral minoxidil comes with potential side effects too. These include: Low blood pressure or high heart rate. Swelling. Weight gain. Enlarged breast tissue in men. Worsening angina (chest pain)
Minoxidil is a prodrug that is converted by sulfation via the sulfotransferase enzyme SULT1A1 to its active form, minoxidil sulfate. The effect of minoxidil is mediated by adenosine, which triggers intracellular signal transduction via both adenosine A 1 receptors and two sub-types of adenosine A 2 receptors (A 2A and A 2B receptors). [26]
Minoxidil sulfate is formed from minoxidil via sulfotransferase enzymes, with the predominant enzyme responsible, at least in hair follicles, being SULT1A1. [1] [2] Minoxidil sulfate acts as a potassium channel opener, among other actions, and has vasodilating, hypotensive, and trichogenic or hypertrichotic (hair growth-promoting) effects.
How Does Minoxidil Work? ... Common Side Effects of Minoxidil Doses. While minoxidil is pretty safe, it has possible adverse effects, like any drug. ... Tachycardia (faster heart rate) Weight gain ...
For example, one study from 1986 focused on the effects of minoxidil on balding around the crown. In the study, 53 percent of participants experienced significant hair growth. ... Heart issues ...
This vasodilation does not decrease the volume of blood the heart pumps, but rather it decreases the force the heart muscle must exert to pump the same volume of blood. Nitroglycerin pills, taken sublingually (under the tongue), are used to prevent or treat acute chest pain.