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Inside of a bone showing the trabecular structure A typical carcinoid tumor of the lung showing a trabecular pattern of elongated groups of cells.. A trabecula (pl.: trabeculae, from Latin for 'small beam') is a small, often microscopic, tissue element in the form of a small beam, strut or rod that supports or anchors a framework of parts within a body or organ.
During bone formation, an osteoblast is left behind and buried in the bone matrix as an "osteoid osteocyte", which maintains contact with other osteoblasts through extended cellular processes. [9] Although recently it was shown that vascular smooth muscle cells drive osteocyte differentiation [ 10 ] , most aspects of osteocytogenesis remain ...
The first step in the process is the formation of bone spicules which eventually fuse with each other and become trabeculae. The periosteum is formed and bone growth continues at the surface of trabeculae. Much like spicules, the increasing growth of trabeculae result in interconnection and this network is called woven bone.
A bone is a rigid organ [1] that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red and white blood cells, store minerals, provide structure and support for the body, and enable mobility.
The mineralized matrix is penetrated by microvessel and numerous osteoblasts. The osteoblasts form new lamellar bone upon the recently exposed surface of the mineralized matrix. This new lamellar bone is in the form of trabecular bone. Eventually, all of the woven bone and cartilage of the original fracture callus is replaced by trabecular bone ...
The endosteum (pl.: endostea) is a thin vascular membrane of connective tissue that lines the inner surface of the bony tissue that forms the medullary cavity of long bones. [ 1 ] [ 2 ] This endosteal surface is usually resorbed during long periods of malnutrition , resulting in less cortical thickness.
The Haversian canal contains the bone's blood supplies. The boundary of an osteon is the cement line. Each Haversian canal is surrounded by varying number (5-20) of concentrically arranged lamellae of bone matrix. Near the surface of the compact bone, the lamellae are arranged parallel to the surface; these are called circumferential lamellae.
The skeleton, often referred to as the skeletal system, is important both as a supporting structure and for maintenance of calcium, phosphate, and acid-base status in the whole organism. [5] The functional part of bone, the bone matrix, is entirely extracellular. The bone matrix consists of protein and mineral. The protein forms the organic matrix.