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Intermediate filaments composed of keratin or desmin are attached to membrane-associated attachment proteins that form a dense plaque on the cytoplasmic face of the membrane. Cadherin molecules form the actual anchor by attaching to the cytoplasmic plaque, extending through the membrane and binding strongly to cadherins coming through the ...
The inner dense plaque, also about 15–20 nm in length, contains the C-terminus end of desmoplakin and their attachment to keratin intermediate filaments. Desmoplakin is the most abundant part of the desmosome, [ 7 ] as it operates as the mediator between the cadherin proteins in the plasma membrane and the keratin filaments.
Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.
The gross anatomy of a muscle is the most important indicator of its role in the body. One particularly important aspect of gross anatomy of muscles is pennation or lack thereof. In most muscles, all the fibers are oriented in the same direction, running in a line from the origin to the insertion.
Complex cells and complex receptive fields, on the other hand have a more complex response that does not exhibit that relationship. The results from the above experiment determined that simple fields have clear excitatory and inhibitory divisions, where light shone on an excitatory region increases the firing of a cell and light shone on an ...
Standard anatomical terms of location are used to describe unambiguously the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position provides a definition of what is at the front ("anterior"), behind ("posterior") and so on.
There are two important foramina, or windows, two important fissures, or grooves, and one canal surrounding the globe in the orbit. There is a supraorbital foramen, an infraorbital foramen, a superior orbital fissure, an inferior orbital fissure and the optic canal, each of which contains structures that are crucial to normal eye functioning.
Biosynthesis, i.e., chemical synthesis occurring in biological contexts, is a term most often referring to multi-step, enzyme-catalyzed processes where chemical substances absorbed as nutrients (or previously converted through biosynthesis) serve as enzyme substrates, with conversion by the living organism either into simpler or more complex ...