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Salbutamol is usually used with an inhaler or nebulizer, but it is also available in a pill, liquid, and intravenous solution. [8] [10] Onset of action of the inhaled version is typically within 15 minutes and lasts for two to six hours. [8] Common side effects include shakiness, headache, fast heart rate, dizziness, and feeling anxious. [8]
Salbutamol/budesonide, sold under the brand name Airsupra, is a fixed-dose combination medication for the treatment of bronchoconstriction and asthma. [ 1 ] [ 2 ] It is a combination of salbutamol sulfate (albuterol sulfate), a short-acting beta2-adrenergic agonist , and budesonide , an inhaled corticosteroid .
Ipratropium bromide/salbutamol, sold under the brand name Combivent among others, is a combination medication used to treat chronic obstructive pulmonary disease (COPD). [1] [4] [5] It contains ipratropium (an anticholinergic) and salbutamol (albuterol, a β 2-adrenergic agonist). [1] Common side effects include sore throat, muscle cramps, and ...
Rarer side effects may indicate a dangerous allergic reaction. These include: paradoxical bronchospasm (shortness of breath and difficulty breathing); skin itching, rash, or hives ( urticaria ); swelling ( angioedema ) of any part of the face or throat (which can lead to voice hoarseness ), or swelling of the extremities.
Nebulizers continuously deliver aerosolized drug and salbutamol delivered through nebulizer was found to be more effective than IV administration. [10] Salbutamol and terbutaline are also both available in oral forms. [11] In addition, several of these medications are available in intravenous forms, including both salbutamol and terbutaline.
[7] [2] It is used by metered-dose manual pump spray. Onset of action is within an hour. [7] Common side effects of inhalant use include dry mouth, cough, inflammation of the airways, [3] and shortness of breath. [8] Potentially serious side effects include urinary retention, worsening spasms of the airways, and a severe allergic reaction. [3]
By treating asthma with optically pure (R)-salbutamol the risk of side effects, such as nervous system stimulatory effects and cardiac arrhythmia, can be minimized. [20] There are several routes for enantioselective synthesis , as well as methods for synthesis of the racemic mixture followed by chiral resolution .
The 2022 Global Initiative for Asthma report [3] recommends a combination formoterol/inhaled corticosteroid inhaler as both a preventer and reliever treatment for asthma in adults. In children, a short-acting β 2 adrenergic agonist (e.g., salbutamol) is still recommended. It was patented in 1972 and came into medical use in 1998. [4]