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Ascending reticular activating system. Reticular formation labeled near center. The ascending reticular activating system (ARAS), also known as the extrathalamic control modulatory system or simply the reticular activating system (RAS), is a set of connected nuclei in the brains of vertebrates that is responsible for regulating wakefulness and ...
The pedunculopontine nucleus (PPN) or pedunculopontine tegmental nucleus (PPT or PPTg) is a collection of neurons located in the upper pons in the brainstem. [1] [2] It is involved in voluntary movements, [3] arousal, and provides sensory feedback to the cerebral cortex and one of the main components of the ascending reticular activating system.
Thanks to the number of different nuclei located within the pontine tegmentum, it is a region associated with a range of functions including sensory and motor functions (due to the cranial nuclei and fiber tracts), control of stages of sleep and levels of arousal and vigilance (due to the ascending cholinergic systems), and some aspects of respiratory control.
Pontocerebellar fibers are the sole efferent pathway of the pontine nuclei. The fibers mostly decussate within the pons to pass through the (contralateral) middle cerebellar peduncle to terminate in the contralateral cerebellum as mossy fibers; they form terminal synapses in the cerebellar cortex, but also issue collaterals to the cerebellar nuclei.
Arousal is the physiological and psychological state of being awoken or of sense organs stimulated to a point of perception. It involves activation of the ascending reticular activating system (ARAS) in the brain, which mediates wakefulness, the autonomic nervous system, and the endocrine system, leading to increased heart rate and blood pressure and a condition of sensory alertness, desire ...
It is a part of the reticular activating system in the reticular formation. [ 3 ] The locus coeruleus, which in Latin means "blue spot", is the principal site for brain synthesis of norepinephrine (noradrenaline).
The tract transmits slow nociceptive/pain information (but thermal, and crude touch information as well) from the spinal cord to reticular formation which in turn relays the information to the thalamus via reticulothalamic fibers as well as to other parts of the brain (as opposed to the spinothalamic tract - the direct pathway of the ...
The paramedian pontine reticular formation (PPRF) is a subset of neurons of the oral and caudal pontine reticular nuclei. With the abducens nucleus it makes up the horizontal gaze centre . [ 1 ] It is situated in the pons adjacent to the abducens nucleus . [ 2 ]