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Bile acid sequestrants are the main agents used to treat bile acid malabsorption. [25] Cholestyramine and colestipol , both in powder form, have been used for many years. Unfortunately, many patients find them difficult to tolerate; although the diarrhea may improve, other symptoms such as abdominal pain and bloating may worsen.
Treatment strategies should focus on identifying and correcting the root causes, where possible, resolving nutritional deficiencies, and administering antibiotics. This is especially important for patients with indigestion and malabsorption. [4] Although whether antibiotics should be a first line treatment is a matter of debate.
Bile acid sequestrants may also be used to treat hyperthyroidism as an adjunct therapy. By inhibiting the enterohepatic circulation, more L-thyroxine will be lost through defecation, thus lowering body thyroxine levels. Cholestyramine has been used in the treatment of Clostridioides difficile infections, in order to absorb toxins A and B.
Treatment: Depends on cause: Malabsorption is a state arising from abnormality in absorption of food nutrients across the gastrointestinal (GI) tract. Impairment can ...
Colestyramine is commonly used to treat diarrhea resulting from bile acid malabsorption. [2] It was first used for this in Crohn's disease patients who had undergone ileal resection. [ 3 ] The terminal portion of the small bowel (ileum) is where bile acids are reabsorbed.
Pancreatic enzymes, also known as pancreases or pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, protease and lactase. [3] [4] They are used to treat malabsorption syndrome due to certain pancreatic problems. [3]
Short bowel syndrome (SBS, or simply short gut) is a rare malabsorption disorder caused by a lack of functional small intestine. [3] The primary symptom is diarrhea, which can result in dehydration, malnutrition, and weight loss. [1]
The "treat empirically" route also has its difficulties, which have all come under wide debate and study. Recommendations are varied but seem to find some common ground around the notion that treatment should be individualized to the specific circumstances under which a patient has developed blind loop syndrome since these circumstances affect ...