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Walter Sutton (left) and Theodor Boveri (right) independently developed different parts of the chromosome theory of inheritance in 1902.. The Boveri–Sutton chromosome theory (also known as the chromosome theory of inheritance or the Sutton–Boveri theory) is a fundamental unifying theory of genetics which identifies chromosomes as the carriers of genetic material.
Walter Stanborough Sutton (April 5, 1877 – November 10, 1916) was an American geneticist and biologist whose most significant contribution to present-day biology was his theory that the Mendelian laws of inheritance could be applied to chromosomes at the cellular level of living organisms. This is now known as the Boveri–Sutton chromosome ...
Thomas Hunt Morgan (September 25, 1866 – December 4, 1945) [2] was an American evolutionary biologist, geneticist, embryologist, and science author who won the Nobel Prize in Physiology or Medicine in 1933 for discoveries elucidating the role that the chromosome plays in heredity.
There are two distinctive mapping approaches used in the field of genome mapping: genetic maps (also known as linkage maps) [7] and physical maps. [3] While both maps are a collection of genetic markers and gene loci, [8] genetic maps' distances are based on the genetic linkage information, while physical maps use actual physical distances usually measured in number of base pairs.
1955: Joe Hin Tjio, while working in Albert Levan's lab, determined the number of chromosomes in humans to be of 46. Tjio was attempting to refine an established technique to separate chromosomes onto glass slides by conducting a study of human embryonic lung tissue, when he saw that there were 46 chromosomes rather than 48.
Image from his textbook The Cell in Development and Inheritance, second edition, 1900. Edmund Beecher Wilson (October 19, 1856 – March 3, 1939) [2] was a pioneering American zoologist and geneticist. He wrote one of the most influential textbooks in modern biology, The Cell. [3] [4] He discovered the chromosomal XY sex-determination system in ...
August Weismann's idea, set out in his 1892 book Das Keimplasma: eine Theorie der Vererbung ("The Germ Plasm: a Theory of Inheritance"), [13] was that the hereditary material, which he called the germ plasm, and the rest of the body (the soma) had a one-way relationship: the germ-plasm formed the body, but the body did not influence the germ ...
The experiments resulted in many important early discoveries in the field, resolved previously unclear issues such as the organization of genetic information within chromosomes, chromosomal arrangement, and linkage in sex chromosomes, and contributed to the emergence of modern treatments of genetics and evolutionary biology from their classical ...