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  2. Clark's level - Wikipedia

    en.wikipedia.org/wiki/Clark's_level

    Levels. Five anatomical levels are recognized, and higher levels have worsening prognostic implications. These levels are: [1] Level 1: Melanoma confined to the epidermis (melanoma in situ) Level 2: Invasion into the papillary dermis. Level 3: Invasion to the junction of the papillary and reticular dermis. Level 4: Invasion into the reticular ...

  3. Wallace H. Clark Jr. - Wikipedia

    en.wikipedia.org/wiki/Wallace_H._Clark_Jr.

    Dermatologist and pathologist. Known for. Research on melanomas. Wallace H. Clark Jr. (May 16, 1924 – November 28, 1997) was an American dermatologist and pathologist. He is best known for devising the "Clark's level", or Clark Level, system for classifying the seriousness of a malignant melanoma skin cancer based on its microscopic appearance.

  4. Breslow's depth - Wikipedia

    en.wikipedia.org/wiki/Breslow's_depth

    Breslow's depth. In medicine, Breslow's depth was used as a prognostic factor in melanoma of the skin. It is a description of how deeply tumor cells have invaded. Currently, the standard Breslow's depth has been replaced by the AJCC depth, in the AJCC staging system of melanoma. Originally, Breslow's depth was divided into 5 stages.

  5. Skin cancer - Wikipedia

    en.wikipedia.org/wiki/Skin_cancer

    Skin cancer is the most common form of cancer, globally accounting for at least 40% of cancer cases. [5] [20] The most common type is nonmelanoma skin cancer, which occurs in at least 2–3 million people per year. [6] [21] This is a rough estimate; good statistics are not kept. [1]

  6. Melanoma - Wikipedia

    en.wikipedia.org/wiki/Melanoma

    59,800 (2015) [6] Melanoma is the most dangerous type of skin cancer; it develops from the melanin -producing cells known as melanocytes. [1] It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma). [1][2] In women, melanomas most commonly occur on the legs; while in men, on the back. [2]

  7. Metastasis - Wikipedia

    en.wikipedia.org/wiki/Metastasis

    Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; [1] the term is typically used when referring to metastasis by a cancerous tumor. [2] The newly pathological sites, then, are metastases (mets). [3][4] It is generally distinguished from cancer invasion, which is ...

  8. Nodular melanoma - Wikipedia

    en.wikipedia.org/wiki/Nodular_melanoma

    Nodular melanoma. Evolution of a 4 mm nodular melanoma. Nodular melanoma (NM) is the most aggressive form of melanoma. [1] It tends to grow more rapidly in thickness (vertically penetrate the skin) than in diameter compared to other melanoma subtypes. [2] Instead of arising from a pre-existing mole, it may appear in a spot where a lesion did ...

  9. Nevoid melanoma - Wikipedia

    en.wikipedia.org/wiki/Nevoid_melanoma

    Nevoid melanoma. A nevoid melanoma is a malignant neoplastic lesion of the skin. It is a type of melanoma, the most dangerous form of skin cancer.Nevoid melanomas are clinically significant because they are difficult to distinguish from a benign nevus of the skin, which requires no treatment and is common on most individuals.

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